Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of therapies in palliative care.
Created June 2007
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| Title: |
Medically assisted hydration for palliative care patients
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
It is common for palliative care patients to have reduced fluid intake during their illness. Management of this condition includes discussion with the patient, family and staff involved and may include the provision of fluids with medical assistance. Th...
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| Date: |
Feb 2008
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| Title: |
Psychotherapy for depression among incurable cancer patients
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Depressive states represent frequent complications among cancer patients and are more common amongst advanced cancer patients. Psychotherapy comprises of various interventions for ameliorating or preventing psychological distress conducted by direct ver...
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| Date: |
Feb 2008
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| Title: |
Palliative endobronchial brachytherapy for non-small cell lung cancer
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Patients with inoperable non-small cell lung cancer (NSCLC) have a poor prognosis and the therapeutic options are limited to controlling their symptoms and maintaining their quality of life. Palliative endobronchial brachytherapy (EBB) is used as a trea...
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| Date: |
Dec 2007
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| Title: |
Interventions for noisy breathing in patients near to death
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Approximately half of those relatives and friends who witness it, as well as hospital staff, find the noise of 'death rattle' distressing. For this reason, doctors and nurses try to eliminate the sound using a variety of methods, from changing the posit...
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| Date: |
Nov 2007
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| Title: |
Methadone for cancer pain
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Pain is a common and debilitating symptom of cancer. Methadone is an opioid drug used to treat cancer pain, and can be given by mouth as liquid, tablet or capsule, via the rectum as a suppository, or injected into the vein, muscle or under the skin. Thi...
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| Date: |
Aug 2007
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| Title: |
Laxatives for the management of constipation in palliative care patients
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Constipation is commonly experienced by palliative care patients as a result of the use of medications, such as opioids for pain control; dietary and mobility factors, as well as disease related factors. This review aimed to determine the effectiveness ...
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| Date: |
Aug 2006
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| Title: |
Palliative radiotherapy regimens for non-small cell lung cancer
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
In most developed countries lung cancer is one of the commonest tumours. Only 10 to 20% of patients can have surgery with a chance of cure. For many of the rest it can be beneficial to treat the tumour in the lung with radiotherapy to relieve symptoms s...
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| Date: |
Aug 2006
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| Title: |
Palliative biliary stents for obstructing pancreatic carcinoma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
The majority of patients with pancreatic cancer present with late stage disease that causes obstruction of the distal biliary tree and jaundice. Surgical by-pass (SBP) or endoscopic stenting (ES) of the malignant obstruction are the treatment options av...
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| Date: |
Jan 2006
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| Title: |
Drug therapy for anxiety in palliative care
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Anxiety is a common symptom associated with patients near the end of life. As with other areas of palliative care, the majority of available literature pertaining to drug therapy for anxiety in terminal illness is anecdotal. A search of the internationa...
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| Date: |
Oct 2003
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| Title: |
Radioisotopes for metastatic bone pain
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Pain is commonly experienced by people whose cancer has spread to their bones. There are several ways to treat this pain, including the administration of radioactive drugs that act on the bone to reduce the effects of the cancer. This review looked at t...
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| Date: |
Aug 2003
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| Title: |
Chemotherapy versus best supportive care for extensive small cell lung cancer
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Small-cell lung cancer accounts for nearly a quarter of all new cases of lung cancer. This cancer is often diagnosed after it has spread to the brain, liver, bone or bone marrow and most patients die in the first year after diagnosis. This review found ...
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| Date: |
Jul 2003
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| Title: |
Ketamine as an adjuvant to opioids for cancer pain
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Morphine-like drugs (opioids) are frequently prescribed for moderate and severe cancer pain, but in some cases these drugs are not effective. Ketamine, an anaesthetic agent, is used to improve analgesia when opioids alone are ineffective. However, evide...
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| Date: |
Oct 2002
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| Title: |
Thermotherapy for treating rheumatoid arthritis
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review found there were no significant effects for hot and ice packs applications and faradic baths on objective measures of disease activity including joint swelling, pain, medication intake, range of motion (ROM), grip strength, hand function or ...
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| Date: |
Dec 2001
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| Title: |
Palliation of metastatic bone pain: single fraction versus multifraction radiotherapy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
The spread of tumour to the bone (metastasis) is a common characteristic of many malignancies including cancers of the prostate, breast and lung. This may be associated with pain, compression of the spinal cord and the potential for bone fracture. Radio...
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| Date: |
Sep 2001
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| Title: |
Second-line chemotherapy for non-small cell lung cancer
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Patients with lung cancer and a good physical condition who have not been cured by a first round of chemotherapy often receive a second round of chemotherapy (second-line). A second round of chemotherapy may not increase the survival chances of these pa...
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| Date: |
Jul 2001
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| Title: |
Benzodiazepines and related drugs for insomnia in palliative care
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Still awaiting evidence about whether benzodiazepines used to aid sleep help or hinder patients with incurable diseases. Benzodiazepines are the drugs most often used to aid sleep. Doctors agree that occassional short-term use can be helpful but do ...
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| Date: |
Jun 2001
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| Title: |
Opioids for the palliation of breathlessness in terminal illness
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Breathlessness is common in people with advanced disease and opioid drugs are often used to treat it. A review to assess the effectiveness of opioids in these patients found a small but statistically significant positive effect when opioids were adminis...
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| Date: |
Apr 2001
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