Systematic Reviews on Complications of Asthma Medications

Follow the links below to find summaries of systematic reviews of the evidence for the possible health complications of asthma medications.

Created February 2009

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28 Resources Found
Results 1 to 20 displayed.
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Title:   Regular treatment with salmeterol and inhaled steroids for chronic asthma: serious adverse events
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   There has been some concern raised at the possibility of increased serious adverse events following administration of salmeterol, a long-acting beta2-agonist, to people with asthma. We analysed data from 30 studies in adults and three in children that c...
Date:   Apr 2009

Title:   Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Previous reviews have found an increase in serious adverse events with both regular formoterol and regular salmeterol in comparison to placebo treatment. This review sought information from trials that compared the two treatments head-to-head. All subje...
Date:   Feb 2009

Title:   Dapsone as an oral corticosteroid sparing agent for asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Some asthma sufferers rely on oral corticosteroids to control their disease. Corticosteroids help reduce the inflammation of the airways associated with asthma. Long-term use of these drugs has serious side effects, so other ways to reduce the need for ...
Date:   Feb 2009

Title:   Chloroquine as a steroid sparing agent for asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Asthma can be treated with drugs which aim to reduce inflammation in the airways. Inhaled corticosteroids are frequently used, but occasionally individuals require oral steroids for adequate control. However, oral steroids are frequently associated with...
Date:   Feb 2009

Title:   Oxatomide for stable asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Oxatomide, an anti-histamine agent, cannot be recommended for the treatment of chronic asthma as there is no consistent data to support a beneficial effect on asthma control. Six randomised controlled studies of the effect of oxatomide were identified. ...
Date:   Sep 2008

Title:   Cyclosporin as an oral corticosteroid sparing agent in stable asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Some people with asthma need to rely on corticosteroid drugs to control their asthma. Corticosteroids help reduce the inflammation (swelling) of the airways (passages to the lungs) associated with asthma. Long-term use of these drugs may have serious ad...
Date:   Sep 2008

Title:   Troleandomycin as an oral corticosteroid sparing agent in stable asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Troleandomycin is a macrolide antibiotic with established effects in the treatment of infections. It alters the breakdown of corticosteroid drugs, so may be of benefit in asthma. This review found three small studies, that provide no evidence to justify...
Date:   Sep 2008

Title:   Gold as an oral corticosteroid sparing agent in stable asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Some people need to rely on corticosteroid drugs to control their asthma. Corticosteroids help reduce the inflammation (swelling) of the airways (passages to the lungs) associated with asthma. Long-term use of these drugs has serious adverse effects, so...
Date:   Sep 2008

Title:   Regular treatment with formoterol for chronic asthma: serious adverse events
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In view of concerns regarding the safety of regular long-acting beta2-agonist inhalers in asthma, this review has gathered all the information available regarding all-cause serious adverse events (both fatal and non-fatal) from clinical trials comparing...
Date:   Aug 2008

Title:   Pneumococcal vaccine for asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Pneumonia is a serious illness for people who have asthma and pneumococcal vaccine has been studied to see if it reduces illness or death in those people. A thorough search for randomised controlled trials of pneumococcal vaccine in asthma has found onl...
Date:   Aug 2008

Title:   Fluticasone at different doses for chronic asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Fluticasone (FP) is an inhaled corticosteroid commonly used to treat inflammation of the airways (passages to the lungs) and improve breathing in people with asthma. This review examined the effectiveness of FP when given at different doses for treating...
Date:   Jul 2008

Title:   Fluticasone versus placebo for chronic asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Fluticasone is a well-established inhaled steroid for use a preventative agent in controlling asthma symptoms. This review found that it is highly effective even in low doses. The effect does appear to increase with higher doses, but these improvements ...
Date:   Jul 2008

Title:   Regular treatment with salmeterol for chronic asthma: serious adverse events
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In view of concerns regarding the safety of regular long-acting beta2-agonist inhalers in asthma, this review has gathered all the information available regarding all-cause serious adverse events (both fatal and non-fatal) from clinical trials comparing...
Date:   Jul 2008

Title:   Azoles for allergic bronchopulmonary aspergillosis associated with asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Allergic Bronchopulmonary Aspergillosis is a condition that complicates some people with chronic asthma. Standard treatment for this condition is high doses of oral steroids. The azole antifungal drugs attack the fungus that causes this condition and sh...
Date:   Jun 2008

Title:   Oral xanthines as maintenance treatment for asthma in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Xanthines (e.g. theophylline) are a group of drugs thought to have helpful preventative and reliever properties in the treatment of asthma in children. This review of studies has established that there is evidence for useful effects of these drugs in te...
Date:   May 2008

Title:   Ciclesonide versus other inhaled steroids for chronic asthma in children and adults
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Inhaled corticosteroids, such as budesonide, beclomethasone or fluticasone, which have been available for many years, have proven to be an important therapy for controlling the inflammation caused by asthma. They are given usually twice daily, and are r...
Date:   Jan 2008

Title:   Long-acting beta2-agonists versus theophylline for maintenance treatment of asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   This review compared three asthma medications, salmeterol, formoterol (both long acting beta-agonists) and theophylline. These medications are used to help control symptoms of asthma, especially those which occur during the night. This review found that...
Date:   Nov 2007

Title:   Nedocromil sodium versus sodium cromoglycate for preventing exercise-induced bronchoconstriction
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Exercise-induced asthma can limit people's endurance, prolong recovery time after exercise, and lead to people avoiding exercise. The episode involves symptoms such as coughing, wheezing, shortness of breath and chest tightness. Two drugs, nedocromil so...
Date:   Oct 2007

Title:   Fluticasone versus beclomethasone or budesonide for chronic asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   This review compares the effectiveness of three inhaled steroids. Fluticasone (FP) was compared with either beclomethasone (BDP) or budesonide (BUD) for treating people with chronic asthma. When FP was given to children or adults at approximately half t...
Date:   Aug 2007

Title:   Cardioselective beta-blockers for reversible airway disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Beta-blockers reduce mortality in patients with hypertension, heart failure and coronary arterial disease. Traditionally they have not been given to patients with reversible airway disease (asthma or chronic obstructive pulmonary disease with a reversib...
Date:   Jun 2007
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