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Follow the links below to find summaries of systematic reviews of the evidence for the possible health complications of asthma medications.
Created February 2009
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| Title: |
Dapsone as an oral corticosteroid sparing agent for asthma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Some asthma sufferers rely on oral corticosteroids to control their disease. Corticosteroids help reduce the inflammation of the airways associated with asthma. Long-term use of these drugs has serious side effects, so other ways to reduce the need for ...
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| Date: |
Feb 2009
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| Title: |
Chloroquine as a steroid sparing agent for asthma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Asthma can be treated with drugs which aim to reduce inflammation in the airways. Inhaled corticosteroids are frequently used, but occasionally individuals require oral steroids for adequate control. However, oral steroids are frequently associated with...
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| Date: |
Feb 2009
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| Title: |
Oxatomide for stable asthma in adults and children
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Oxatomide, an anti-histamine agent, cannot be recommended for the treatment of chronic asthma as there is no consistent data to support a beneficial effect on asthma control. Six randomised controlled studies of the effect of oxatomide were identified. ...
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| Date: |
Sep 2008
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| Title: |
Cyclosporin as an oral corticosteroid sparing agent in stable asthma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Some people with asthma need to rely on corticosteroid drugs to control their asthma. Corticosteroids help reduce the inflammation (swelling) of the airways (passages to the lungs) associated with asthma. Long-term use of these drugs may have serious ad...
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| Date: |
Sep 2008
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| Title: |
Troleandomycin as an oral corticosteroid sparing agent in stable asthma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Troleandomycin is a macrolide antibiotic with established effects in the treatment of infections. It alters the breakdown of corticosteroid drugs, so may be of benefit in asthma. This review found three small studies, that provide no evidence to justify...
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| Date: |
Sep 2008
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| Title: |
Gold as an oral corticosteroid sparing agent in stable asthma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Some people need to rely on corticosteroid drugs to control their asthma. Corticosteroids help reduce the inflammation (swelling) of the airways (passages to the lungs) associated with asthma. Long-term use of these drugs has serious adverse effects, so...
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| Date: |
Sep 2008
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| Title: |
Regular treatment with formoterol for chronic asthma: serious adverse events
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
In view of concerns regarding the safety of regular long-acting beta2-agonist inhalers in asthma, this review has gathered all the information available regarding all-cause serious adverse events (both fatal and non-fatal) from clinical trials comparing...
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| Date: |
Aug 2008
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| Title: |
Pneumococcal vaccine for asthma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Pneumonia is a serious illness for people who have asthma and pneumococcal vaccine has been studied to see if it reduces illness or death in those people. A thorough search for randomised controlled trials of pneumococcal vaccine in asthma has found onl...
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| Date: |
Aug 2008
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| Title: |
Fluticasone at different doses for chronic asthma in adults and children
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Fluticasone (FP) is an inhaled corticosteroid commonly used to treat inflammation of the airways (passages to the lungs) and improve breathing in people with asthma. This review examined the effectiveness of FP when given at different doses for treating...
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| Date: |
Jul 2008
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| Title: |
Fluticasone versus placebo for chronic asthma in adults and children
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Fluticasone is a well-established inhaled steroid for use a preventative agent in controlling asthma symptoms. This review found that it is highly effective even in low doses. The effect does appear to increase with higher doses, but these improvements ...
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| Date: |
Jul 2008
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| Title: |
Regular treatment with salmeterol for chronic asthma: serious adverse events
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
In view of concerns regarding the safety of regular long-acting beta2-agonist inhalers in asthma, this review has gathered all the information available regarding all-cause serious adverse events (both fatal and non-fatal) from clinical trials comparing...
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| Date: |
Jul 2008
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| Title: |
Azoles for allergic bronchopulmonary aspergillosis associated with asthma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Allergic Bronchopulmonary Aspergillosis is a condition that complicates some people with chronic asthma. Standard treatment for this condition is high doses of oral steroids. The azole antifungal drugs attack the fungus that causes this condition and sh...
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| Date: |
Jun 2008
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| Title: |
Oral xanthines as maintenance treatment for asthma in children
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Xanthines (e.g. theophylline) are a group of drugs thought to have helpful preventative and reliever properties in the treatment of asthma in children. This review of studies has established that there is evidence for useful effects of these drugs in te...
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| Date: |
May 2008
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| Title: |
Ciclesonide versus other inhaled steroids for chronic asthma in children and adults
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Inhaled corticosteroids, such as budesonide, beclomethasone or fluticasone, which have been available for many years, have proven to be an important therapy for controlling the inflammation caused by asthma. They are given usually twice daily, and are r...
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| Date: |
Jan 2008
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| Title: |
Long-acting beta2-agonists versus theophylline for maintenance treatment of asthma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review compared three asthma medications, salmeterol, formoterol (both long acting beta-agonists) and theophylline. These medications are used to help control symptoms of asthma, especially those which occur during the night. This review found that...
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| Date: |
Nov 2007
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| Title: |
Fluticasone versus beclomethasone or budesonide for chronic asthma in adults and children
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review compares the effectiveness of three inhaled steroids. Fluticasone (FP) was compared with either beclomethasone (BDP) or budesonide (BUD) for treating people with chronic asthma. When FP was given to children or adults at approximately half t...
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| Date: |
Aug 2007
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| Title: |
Cardioselective beta-blockers for reversible airway disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Beta-blockers reduce mortality in patients with hypertension, heart failure and coronary arterial disease. Traditionally they have not been given to patients with reversible airway disease (asthma or chronic obstructive pulmonary disease with a reversib...
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| Date: |
Jun 2007
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