Systematic Reviews on Bacterial Infections

Follow the links below to find systematic reviews of the evidence for the effectiveness of interventions for bacterial infections.

Created January 2008

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39 Resources Found
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Title:   Face washing promotion for preventing active trachoma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Trachoma is an infectious eye disease. Active infection usually begins in childhood and is characterised by eye discharges, redness and irritation. Poor facial hygiene can lead to the disease spreading from person to person through eye-seeking flies or ...
Date:   Mar 2004

Title:   Antibiotic prophylaxis for bacterial infections in afebrile neutropenic patients following chemotherapy
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The first sign of infection may be fever with the accompanying risks of morbidity (illness) and mortality. Without preventive measures, 48% to 60% of cancer patients who become feverish have an established infection. Antibiotic prophylaxis (prevention) ...
Date:   Jul 2005

Title:   G-CSF and GM-CSF for treating or preventing neonatal infections
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Objectives: To determine the efficacy and safety of the haemopoietic colony stimulating factors (G-CSF or GM-CSF) in newborn infants, when used for: a) treatment of suspected or proven systemic infection to reduce mortality, or b) prophylaxis, to prevent systemic infection in infants at high risk of nosocomial infection.

Title:   Antimicrobial drugs for treating methicillin-resistant Staphylococcus aureus colonization
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Staphylococcus aureus is a bacterium that can cause serious infections. Methicillin-resistant S. aureus (MRSA) refers to strains of S. aureus that are resistant to many antibiotics including the penicillins. Hospital infection control staff want to lim...
Date:   Aug 2003

Title:   Elective versus symptomatic intravenous antibiotic therapy for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Chronic infection of the airways by Pseudomonas aeruginosa in people with cystic fibrosis is associated with deterioration in respiratory function. Intravenous antibiotics are the standard therapy for pulmonary exacerbations caused by this micro-organis...
Date:   Aug 2001

Title:   Penicillins for the prophylaxis of bacterial endocarditis in dentistry
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   There is a lack of evidence to support published guidelines in this area. It is not clear whether the potential harms and costs of penicillin administration outweigh any beneficial effect. Ethically practitioners need to discuss the potential benefits a...
Date:   Feb 2004

Title:   Antibiotics for preventing leptospirosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Leptospirosis is an infectious disease transmitted by animals. Two randomised clinical trials have examined doxycycline for preventing leptospirosis. One of the trials had excellent methodological quality, but only studied male soldiers during jungle tr...
Date:   Aug 2000

Title:   Methods of preventing bacterial sepsis and wound complications for liver transplantation
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Bacterial sepsis and wound complications after liver transplantation increase mortality, morbidity, hospital stay, and overall transplant costs. Various methods have been attempted to decrease the bacterial sepsis and wound complications. A total of sev...
Date:   Feb 2008

Title:   Interventions for treating melioidosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Melioidosis is an infectious disease that occurs in tropical regions, particularly in Thailand. It is caused by the bacterium Burkholderia pseudomallei and is a serious condition which can be fatal. Beta-lactam antibiotics have dramatically reduced the risk of death, but mortality still remains high.

Title:   Antibiotic regimens for endometritis after delivery
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Inflammation of the lining of the womb (postpartum endometritis), also known as puereral fever, is caused by infection entering the womb (uterus) during childbirth. It occurs in about 1% to 3% of births, and is up to ten times more common after caesarea...
Date:   Jul 2004

Title:   Topical corticosteroids as adjunctive therapy for bacterial keratitis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Bacterial keratitis or corneal inflammation due to bacterial infection, is a potentially sight threatening condition. Risk factors for bacterial keratitis, a serious ocular condition that can result in visual disability, include contact lens wear, ocula...
Date:   Aug 2007

Title:   Corticosteroids for treating nerve damage in leprosy
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Leprosy is a chronic infectious disease. Leprosy bacteria cause damage to skin and peripheral nerves which can result in nerve function impairment and disability. Corticosteroids, especially prednisolone, are commonly used for treating nerve damage alth...
Date:   Feb 2007

Title:   Antibiotic regimens for secondary peritonitis of gastrointestinal origin in adults
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Antibiotics are effective in preventing post-operative complications following infection of the peritoneum (peritonitis), but there is no evidence to support that one regimen is superior to another, and at the same time has less side effects.Patients wi...
Date:   Jan 2005

Title:   Inhaled corticosteroids for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Post-infection inflammation may contribute to lung damage; long term the most common cause of death in cystic fibrosis (CF). Corticosteroids treat inflammation but may cause adverse effects. These are more severe with oral corticosteroids, but may occur...
Date:   Oct 1999

Title:   Additional anti-Gram-positive antibiotic treatment for febrile neutropenic cancer patients
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Resistant Gram-positive bacteria, originating from the skin and breaks in skin integrity such as intravenous lines, have emerged as causes for infection in cancer patients. Specific antibiotics must be added to the 'standard' antibiotic regimen to cover...
Date:   Apr 2005

Title:   Combination antimicrobial susceptibility testing for acute exacerbations in chronic infection of Pseudomonas aeruginosa in cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The main cause of death in people with cystic fibrosis (CF) is due to chronic lung infection. People with CF now live longer due to the aggressive use of antibiotics to treat lung infections. Traditionally, antibiotics are chosen based on the results of...
Date:   Jul 2008

Title:   Interventions for skin changes caused by nerve damage in leprosy
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Three million persons are affected by nerve damage caused by leprosy (Hansen's disease) worldwide. Leprosy is a chronic infectious disease caused by the bacterium Mycobacterium leprae. About 30% of people with leprosy develop nerve damage that can lead ...
Date:   Jul 2008

Title:   Vaccines for preventing infection with Pseudomonas aeruginosa in people with cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cystic fibrosis is a hereditary disease which causes excessive production of thick mucus in the lungs. Chronic lung infections are caused by Pseudomonas aeruginosa and other bacteria which result in permanent lung damage. Only one small trial has been c...
Date:   Nov 1998

Title:   Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   People with advanced kidney disease may be treated with peritoneal dialysis where a catheter is permanently inserted into the peritoneum (lining around abdominal contents) through the abdominal wall and sterile fluid is drained in and out a few times ea...
Date:   Jul 2004

Title:   Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cystic fibrosis blocks the airways with mucus and causes frequent respiratory infections, which may lead to death from breathing failure. A germ called Pseudomonas aeruginosa is a frequent cause of infection. We found that nebulised antibiotics (or a co...
Date:   Nov 2005
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