Systematic Reviews of Treatments for Stroke

Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of treatments, other than rehabilitation, for stroke.

For summaries of systematic reviews of the evidence for the effectiveness of rehabilitation interventions for stroke, go to Systematic Reviews on Stroke Rehabilitation [HealthInsite Topic Page]

Updated January 2009

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50 Resources Found
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Title:   Effect of early treatment with anti-hypertensive drugs on short and long-term mortality in patients with an acute cardiovascular event
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Reducing blood pressure with drugs has been a strategy used in patients suffering from an acute event in the heart or in the brain, such as heart attack or stroke. There is controversy whether these drugs should be used in the immediate period of these ...
Date:   Aug 2009

Title:   Piracetam for acute ischaemic stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Ischaemic stroke is the third leading cause of death in developed countries, and the first leading cause of long-term disability in survivors. Piracetam is a drug which has been marketed by drug companies in several countries for many years as a 'nootro...
Date:   Oct 2008

Title:   Mailuoning for acute ischaemic stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Mailuoning, a type of Chinese traditional medicine, is widely used in the treatment of acute ischaemic stroke in China even though its efficacy is still uncertain. Animal experimental studies and clinical pharmacological research indicate that mailuonin...
Date:   Sep 2008

Title:   Sanchi for acute ischaemic stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Sanchi is one of the most widely used medicinal herbs in China but the present evidence does not allow a conclusion to support its routine use for acute ischaemic stroke. There are very few drugs supported for routine use for acute ischaemic stroke by c...
Date:   Jun 2008

Title:   Aspirin for vascular dementia
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Vascular dementia results from changes in the blood supply to the brain. This may occur from blockages in the arterial and/or capillary systems. Aspirin decreases TXA2 synthesis without significantly reducing prostacyclin synthesis thus causing reduced ...
Date:   May 2008

Title:   Chuanxiong-type preparations for acute ischemic stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Stroke is a common disorder. It is due either to blockage of an artery in the brain or to bleeding in the brain. Chuanxiong is a Traditional Chinese Medicine. It is widely used in China for the treatment of patients with stroke. Two poor quality trials ...
Date:   Apr 2008

Title:   Interventions for deliberately altering blood pressure in acute stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In patients who have just had a stroke (a sudden brain attack either due to blockage or rupture of an artery in the brain), very high and very low blood pressures may be harmful. Drugs which raise low blood pressure or lower high blood pressure might be...
Date:   Apr 2008

Title:   Tongxinluo capsule for acute stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Traditional Chinese medicine is often used to treat patients with acute ischaemic stroke. The authors undertook a systematic review of the potential benefits and safety of tongxinluo capsule used for the treatment of patients with acute ischaemic stroke...
Date:   Mar 2008

Title:   Dengzhanhua preparations for acute cerebral infarction
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   There is no clear evidence that dengzhanhua injections benefit patients with acute cerebral infarction. Dengzhanhua preparations are a traditional herbal drug that are commonly used in China to treat disorders of the blood supply to the heart and brain,...
Date:   Mar 2008

Title:   Cooling therapy for acute stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Stroke is a life-threatening event in which part of the brain stops functioning properly, because it either does not receive blood and oxygen or it is damaged by bleeding from a ruptured blood vessel. Interventions to reduce temperature may protect brai...
Date:   Feb 2008

Title:   Acanthopanax for acute ischaemic stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Most strokes take place when a blood clot blocks a blood vessel leading to the brain. Without a proper blood supply, the brain quickly suffers damage, which can be permanent. The damage from a stroke can cause arm or leg weakness, or difficulties with l...
Date:   Jan 2008

Title:   Anticoagulants for acute ischaemic stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Millions of people around the world have strokes every year. Most strokes take place when a blood clot blocks a blood vessel leading to the brain. Without a proper blood supply, the brain quickly suffers damage, which can be permanent. The damage from a...
Date:   Jan 2008

Title:   Surgery for primary supratentorial intracerebral haemorrhage
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   There is evidence of benefit from surgical removal of the blood clot formed after a stroke due to bleeding in the brain. Most strokes are due to the blockage of an artery to one part of the brain; these are called ischaemic strokes. Some strokes occur b...
Date:   Dec 2007

Title:   Antiplatelet therapy for acute ischaemic stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Most strokes are caused by a sudden blockage of an artery in the brain (called an ischaemic stroke) that is usually due to a blood clot. Immediate treatment with antiplatelet drugs such as aspirin may prevent new clots from forming and hence improve rec...
Date:   Sep 2007

Title:   Low-molecular-weight heparins or heparinoids versus standard unfractionated heparin for acute ischaemic stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The commonest type of stroke is an ischaemic stroke. It is due to a sudden blockage of an artery to the brain. Blood thinning drugs (anticoagulants), including heparin or heparinoids, can help clear blocked arteries, prevent reblockage, and prevent post...
Date:   Sep 2007

Title:   Vinpocetine for acute ischaemic stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Stroke is a life-threatening event in which part of the brain does not receive enough oxygen, usually because of a blood clot blocking an artery in the brain. Stroke is the third leading cause of death and is an important cause of long-term disability. ...
Date:   May 2007

Title:   Naftidrofuryl for acute stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Stroke is the third most common cause of death and the commonest cause of disability in the western world. Stroke greatly adds to the burden on patients, carers, medical practitioners and health resources. The development of drugs to limit brain damage ...
Date:   Dec 2006

Title:   Calcium antagonists for aneurysmal subarachnoid haemorrhage
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   A subarachnoid haemorrhage is a bleed in the so-called subarachnoid space, which is the very small space between the brain and the skull, and which contains blood vessels that supply the brain. The cause of the bleeding usually is a rupture of a bulge i...
Date:   Oct 2006

Title:   Puerarin for acute ischaemic stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Puerarin, a form of herbal medicine, is widely used in China. We reviewed evidence from randomised or quasi-randomised controlled trials investigating puerarin in patients with acute ischaemic stroke. This review of one trial, involving 98 participants,...
Date:   Oct 2006

Title:   Amphetamines for improving recovery after stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   A stroke interrupts the blood flow to the brain, often leading to damage to some functions of the brain. This can cause persisting paralysis of some parts of the body or other difficulties with various physical functions. Experiments in animals have sho...
Date:   Sep 2006
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