Systematic Reviews of Treatments for Respiratory Conditions in Babies

Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of treatments for respiratory conditions in babies.

Created April 2009

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99 Resources Found
Results 1 to 20 displayed.
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Title:   Protein-containing synthetic surfactant versus protein-free synthetic surfactant for the prevention and treatment of respiratory distress syndrome
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Respiratory distress syndrome (RDS) is a significant cause of illness in preterm infants. RDS is caused by a deficiency or a dysfunction of the chemicals that line the lung, called pulmonary surfactant. Numerous preparations that contain surfactants of ...
Date:   Jun 2009
Title:   Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   When people in intensive care need assistance breathing, they may need to have a breathing tube inserted down through their windpipe (trachea or airway - the passage to the lungs). After it is taken out (extubation), the airways can be swollen (inflamed...
Date:   May 2009
Title:   Animal derived surfactant extract for treatment of respiratory distress syndrome
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Respiratory distress syndrome (RDS) is caused by a deficiency or dysfunction of the lining chemicals of the lung known as pulmonary surfactant. A wide variety of surfactant products have been formulated and studied in clinical trials. These include synt...
Date:   Feb 2009
Title:   High frequency oscillatory ventilation versus conventional ventilation for infants with severe pulmonary dysfunction born at or near term
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Pulmonary disease is a major cause of mortality and morbidity in term and near term infants. Conventional ventilation (CV) has been used for many years but may lead to lung injury, require the subsequent use of more invasive treatment such as extra corporeal membrane oxygenation (ECMO), or result in death.
Title:   Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   High frequency oscillatory ventilation is a way of providing artificial ventilation of the lungs that theoretically may produce less injury to the lungs and therefore reduce the rate of chronic lung disease. This review of the evidence from fifteen rand...
Date:   Feb 2009
Title:   Digoxin for preventing or treating neonatal respiratory distress syndrome
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Sometimes a newborn baby has lungs that are not expanded properly. This is most common in preterm babies (born before 34 weeks) and is known as respiratory distress syndrome (RDS). Congestive heart failure may lead to fluid accumulation in the lungs, c...
Date:   Jan 2009
Title:   Moderately early (7-14 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Moderately early use of steroids helps to get preterm babies off ventilators, reduces chronic lung disease, and may also improve survival to 28 days, but there are important short term adverse effects. Chronic lung disease (CLD) is usually caused by a p...
Date:   Nov 2008
Title:   Newborn screening for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In people with cystic fibrosis lung disease and malnutrition occur very early in life. These complications are suited to early treatment. Newborn screening may therefore improve outcomes for people with cystic fibrosis. We aimed to find out whether newb...
Date:   Nov 2008
Title:   Prophylactic anti-staphylococcal antibiotics for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cystic fibrosis blocks the airways with mucus and causes frequent respiratory infections, which may lead to death from breathing failure. People with cystic fibrosis are sometimes given antibiotics regularly in an attempt to prevent infections. However,...
Date:   Nov 2008
Title:   Multiple versus single doses of exogenous surfactant for the prevention or treatment of neonatal respiratory distress syndrome
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Surfactant is essential to normal lung function in babies. Respiratory distress syndrome (RDS) is caused by a lack of, or dysfunction in, surfactant. A variety of surfactants have been manufactured, and are given to babies at risk of RDS. The review ...
Date:   Nov 2008
Title:   Late (©7 days) postnatal corticosteroids for chronic lung disease in preterm infants
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The benefits of late corticosteroid therapy in preterm babies may not outweigh actual or potential adverse effects.
Date:   Nov 2008
Title:   Early (>8 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Chronic lung disease (CLD) is a major problem for newborn babies in neonatal intensive care units. Persistent inflammation of the lungs is the most likely cause. Corticosteroid drugs have been used to either prevent or treat CLD because of their strong ...
Date:   Sep 2008
Title:   Gradual versus abrupt discontinuation of oxygen in preterm or low birth weight infants
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Babies born either prematurely (before 37 weeks) or with a low birthweight often have breathing problems and need extra oxygen. Accurate oxygen levels are important as damage to the eyes or lungs can result if levels are wrong. The decision to stop givi...
Date:   Aug 2008
Title:   Early versus late discontinuation of oxygen in preterm or low birth weight infants
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Babies born either prematurely (before 37 weeks) or with a low birthweight often have breathing problems and need extra oxygen. Oxygen supplementation has provided many benefits for these babies and the ability to measure oxygen levels accurately can he...
Date:   Aug 2008
Title:   Restricted versus liberal oxygen exposure for preventing morbidity and mortality in preterm or low birth weight infants
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Babies born either prematurely (before 37 weeks) or with a low birthweight often have breathing problems and need extra oxygen. Oxygen supplementation has provided many benefits for these babies but can cause damage to the eyes (retinopathy) and lungs. ...
Date:   Aug 2008
Title:   Positioning for acute respiratory distress in hospitalised infants and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Infants and children with respiratory distress may be more comfortable and breathe more easily when placed in positions other than lying on their back such as being supported over someone's shoulder, sitting upright or on their front with their legs ben...
Date:   Aug 2008
Title:   Prophylactic caffeine to prevent postoperative apnea following general anesthesia in preterm infants
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Caffeine may be able to prevent postoperative apnea and bradycardia in preterm babies. Growing babies who were born too early (preterm) and who undergo general anaesthetic for surgery may have complications, including episodes of apnea (pauses in breath...
Date:   Jul 2008
Title:   Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   There is some evidence that nasal intermittent positive pressure ventilation (NIPPV) increases the effectiveness of nasal continuous positive airway pressure (NCPAP) in preterm babies who no longer need an endotracheal tube (tube in the wind pipe). Pret...
Date:   Jun 2008
Title:   Prophylactic methylxanthine for prevention of apnea in preterm infants
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Based on the current trials, there is no evidence to show the benefit of using caffeine to prevent apnea in premature babies considered at risk. Apnea is a pause in breathing of greater than 20 seconds. It may occur repeatedly in preterm babies (born be...
Date:   Jun 2008
Title:   Continuous distending pressure for respiratory distress in preterm infants
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Respiratory distress syndrome (RDS) is the most common cause of disease and death in babies before 34 weeks. Intermittent positive pressure ventilation (IPPV) is the standard way of helping these babies breathe. A simpler method of assisting breathing i...
Date:   May 2008
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