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Follow the links below to find systematic reviews of the evidence for the effectiveness of treatments for Parkinson's Disease.
Reviewed March 2009
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| Title: |
Dopamine agonist therapy in early Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This 'umbrella' meta-analysis assesses dopamine agonists as a drug class in early Parkinson's disease. Twenty-nine eligible trials, involving 5247 participants, were identified. It confirms reports from individual trials that motor complications are red...
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| Date: |
Jan 2008
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| Title: |
Bromocriptine/levodopa combined versus levodopa alone for early Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Parkinson's disease is a disabling condition characterised by slowness of movement, trembling (tremors) and stiffness. Currently, the best treatment is levodopa. However, according to the number of levodopa treatment years, new disabling fluctuations of...
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| Date: |
Aug 2007
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| Title: |
Bromocriptine versus levodopa in early Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Parkinson's disease is a disabling disease characterized by slowness of movement, trembling (tremors) and stiffness. Currently, the best treatment for Parkinson's disease is levodopa. However, with the number of levodopa treatment years, new disabling f...
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| Date: |
Aug 2007
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| Title: |
Occupational therapy for patients with Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Parkinson's disease is a progressive disabling neurodegenerative disease. Symptoms can include problems with movement such as being stiff, slow, and shaky, and sometimes non-motor symptoms such as problems with communication, mood, vision, and problem s...
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| Date: |
May 2007
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| Title: |
Therapies for depression in Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Parkinson's disease can lead to psychiatric as well as physical symptoms, the most common of which is depression. Oral antidepressants, electroconvulsive therapy or behavioural therapy are currently used in the treatment of depression in Parkinson's dis...
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| Date: |
Feb 2003
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| Title: |
Amantadine for dyskinesia in Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Levodopa is regarded as the most effective treatment for Parkinson's disease but in many patients it causes abnormal involuntary movements known as dyskinesias. It is thought that amantadine may be added to levodopa to reduce dyskinesias in patients wit...
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| Date: |
Jan 2003
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| Title: |
Beta-blocker therapy for tremor in Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Tremor is one of the main symptoms of Parkinson's disease, and it can be embarrassing and limit daily activities. The drugs most commonly used for Parkinson's disease tend to be more effective in treating other symptoms of the disease (such as rigidity ...
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| Date: |
Sep 2002
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| Title: |
Amantadine in Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Parkinson's disease causes progressive muscle rigidity, tremors and other symptoms. The most common drug used to try and relieve these symptoms is levodopa, but serious physical and psychiatric adverse effects are common. Amantadine is another option, u...
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| Date: |
Sep 2002
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| Title: |
Anticholinergics for symptomatic management of Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Anticholinergics were the first drugs available for Parkinson's disease and they are still widely used. They are believed to work by counteracting an imbalance which exists in Parkinson's disease between two chemicals in the brain which transmit message...
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| Date: |
May 2002
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| Title: |
Physiotherapy versus placebo or no intervention in Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review will compare the benefits of physiotherapy versus placebo (sham treatment) or no treatment for people with Parkinson's disease. Relevant trials were found by electronic searches of 21 medical literature databases, various registers of clinic...
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| Date: |
Mar 2001
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| Title: |
Physiotherapy for Parkinson's disease: a comparison of techniques
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review will compare the benefits of one form of physiotherapy versus another for people with Parkinson's disease. Relevant trials were identified by electronic searches of 21 medical literature databases, various registers of clinical trials and an...
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| Date: |
Nov 2000
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| Title: |
Non-pharmacological therapies for dysphagia in Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review compared the benefits of swallowing therapy versus placebo (sham therapy) or no therapy for swallowing disorders in Parkinson's disease. Relevant trials were identified by electronic searches of 21 medical literature databases, various regis...
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| Date: |
Nov 2000
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| Title: |
Ropinirole for levodopa-induced complications in Parkinson's disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Three trials have compared ropinirole with an inactive placebo in 263 patients in the later stages of Parkinson's disease. Two studies were relatively small, were conducted over the short term (12 weeks), and used relatively low doses of ropinirole (max...
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| Date: |
Nov 2000
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