Systematic Reviews of Treatments for Parkinson's Disease

Follow the links below to find systematic reviews of the evidence for the effectiveness of treatments for Parkinson's Disease.

Created December 2007

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27 Resources Found
Results 1 to 20 displayed.
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Title:   Bromocriptine versus levodopa in early Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Parkinson's disease is a disabling disease characterized by slowness of movement, trembling (tremors) and stiffness. Currently, the best treatment for Parkinson's disease is levodopa. However, with the number of levodopa treatment years, new disabling f...
Date:   Aug 2007
Title:   Dopamine agonist therapy in early Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Dopamine agonist therapy in early Parkinson's disease. This 'umbrella' meta-analysis assesses dopamine agonists as a drug class in early Parkinson's disease. Twenty-nine eligible trials, involving 5247 participants, were identified. It confirms reports ...
Date:   Apr 2008
Title:   Beta-blocker therapy for tremor in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Tremor is one of the main symptoms of Parkinson's disease, and it can be embarrassing and limit daily activities. The drugs most commonly used for Parkinson's disease tend to be more effective in treating other symptoms of the disease (such as rigidity ...
Date:   Sep 2002
Title:   Occupational therapy for patients with Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Parkinson's disease is a progressive disabling neurodegenerative disease. Symptoms can include problems with movement such as being stiff, slow, and shaky, and sometimes non-motor symptoms such as problems with communication, mood, vision, and problem s...
Date:   May 2007
Title:   Anticholinergics for symptomatic management of Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Anticholinergics were the first drugs available for Parkinson's disease and they are still widely used. They are believed to work by counteracting an imbalance which exists in Parkinson's disease between two chemicals in the brain which transmit message...
Date:   May 2002
Title:   Physiotherapy for Parkinson's disease: a comparison of techniques
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   This review will compare the benefits of one form of physiotherapy versus another for people with Parkinson's disease. Relevant trials were identified by electronic searches of 21 medical literature databases, various registers of clinical trials and an...
Date:   Nov 2000
Title:   Therapies for depression in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Parkinson's disease can lead to psychiatric as well as physical symptoms, the most common of which is depression. Oral antidepressants, electroconvulsive therapy or behavioural therapy are currently used in the treatment of depression in Parkinson's dis...
Date:   Feb 2003
Title:   Physiotherapy versus placebo or no intervention in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   This review will compare the benefits of physiotherapy versus placebo (sham treatment) or no treatment for people with Parkinson's disease. Relevant trials were found by electronic searches of 21 medical literature databases, various registers of clinic...
Date:   Mar 2001
Title:   Amantadine in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Parkinson's disease causes progressive muscle rigidity, tremors and other symptoms. The most common drug used to try and relieve these symptoms is levodopa, but serious physical and psychiatric adverse effects are common. Amantadine is another option, u...
Date:   Sep 2002
Title:   Catechol-O-methyltransferase inhibitors for levodopa-induced complications in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   As Parkinson's disease progresses the control of the symptoms often requires the addition of other drugs to levodopa. The principle aim of COMT inhibitor therapy is to increase the duration of effect of each levodopa dose and thus reduce the time patien...
Date:   Jun 2004
Title:   Amantadine for dyskinesia in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Levodopa is regarded as the most effective treatment for Parkinson's disease but in many patients it causes abnormal involuntary movements known as dyskinesias. It is thought that amantadine may be added to levodopa to reduce dyskinesias in patients wit...
Date:   Jan 2003
Title:   Non-pharmacological therapies for dysphagia in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   This review compared the benefits of swallowing therapy versus placebo (sham therapy) or no therapy for swallowing disorders in Parkinson's disease. Relevant trials were identified by electronic searches of 21 medical literature databases, various regis...
Date:   Nov 2000
Title:   Speech and language therapy for dysarthria in Parkinson's disease: a comparison of techniques
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   This review will compare the benefits of one form of speech and language therapy versus another for individuals with Parkinson's disease. Relevant trials were identified by electronic searches of 21 biomedical literature databases, various registers of ...
Date:   Feb 2001
Title:   Lisuride versus bromocriptine for levodopa-induced complications in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Long-term levodopa therapy in Parkinson's disease is associated with the development of motor complications including abnormal involuntary movements and a shortening response to each dose (wearing off phenomenon).
Title:   Lisuride for levodopa-induced complications in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Long-term levodopa therapy in Parkinson's disease is associated with the development of motor complications including abnormal involuntary movements and a shortening response to each dose (wearing off phenomenon).
Title:   Ropinirole versus bromocriptine for levodopa-induced complications in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Three trials have compared ropinirole with bromocriptine in 482 patients in the later stages of Parkinson's disease. Two studies were conducted over the short term (8 and 16 weeks), and used relatively low doses of ropinirole (9 mg/d) and bromocriptine ...
Date:   Nov 2000
Title:   Speech and language therapy versus placebo or no intervention for dysarthria in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   This review will compare the benefits of speech and language therapy versus placebo (sham therapy) or no treatment for speech disorders in Parkinson's disease. Relevant trials were identified by electronic searches of 21 medical literature databases, va...
Date:   Feb 2001
Title:   Catechol-O-methyltransferase inhibitors versus active comparators for levodopa-induced complications in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   As Parkinson's disease progresses the control of the symptoms often requires the addition of other drugs to levodopa. The principle aim of COMT inhibitor therapy is to increase the duration of effect of each levodopa dose and thus reduce the time patien...
Date:   Jun 2004
Title:   Pramipexole for levodopa-induced complications in Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Four trials have compared pramipexole with placebo in 669 patients with later Parkinson's disease. Two studies were medium term (24 weeks) and 2 studies were short term (4 weeks). Pramipexole significantly reduced the time patients spent in the immobile...
Date:   Jan 2000
Title:   Bromocriptine/levodopa combined versus levodopa alone for early Parkinson's disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Bromocriptine/levodopa combination therapy versus levodopa alone for early Parkinson's diseaseParkinson's disease is a disabling condition characterised by slowness of movement, trembling (tremors) and stiffness. Currently, the best treatment is levodop...
Date:   Aug 2007
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