Systematic Reviews of Treatments for High Blood Pressure

Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of treatments for managing high blood pressure.
Reviewed September 2009

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39 Resources Found
Results 1 to 20 displayed.
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Title:   Blood pressure lowering efficacy of reserpine for primary hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Reserpine, a root extract of the naturally occurring plant Rauwolfia serpentina, was used in the past as first-line therapy for reducing blood pressure. Nowadays, it is used mainly as a second line agent. This review, which aimed to find and summarize e...
Date:   Aug 2009
Title:   Blood pressure lowering efficacy of loop diuretics for primary hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Loop diuretics are more commonly used to reduce water retention, but are also indicated to lower elevated blood pressure. We asked how much this class of drugs lowers blood pressure and whether there is a difference between individual drugs within the c...
Date:   Aug 2009
Title:   Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Coenzyme Q10 has been studied as a potential treatment for hypertension, a common medical condition. However, there is not enough reliable evidence to show whether or not it can be a useful medication to lower blood pressure. A systematic review was con...
Date:   Aug 2009
Title:   Blood pressure lowering efficacy of alpha blockers for primary hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The class of drugs called alpha blockers is sometimes used to lower elevated blood pressure. This class includes drugs such as doxazosin (brand name: Cardura), prazosin (Minipress) and terazosin (Hytrin). We asked how much this class of drugs lowers blo...
Date:   Aug 2009
Title:   Methyldopa for primary hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Methyldopa is a medication that has been used to treat high blood pressure since the 1960s. While there is some belief methyldopa reduces blood pressure, there are concerns due to the potential for this drug to cause adverse effects. The aim of this rev...
Date:   Aug 2009
Title:   Long-term effects of weight-reducing drugs in hypertensive patients
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   For overweight patients with elevated blood pressure doctors often recommend weight reduction. Drugs such as orlistat, sibutramine or rimonabant are sometimes suggested to assist in weight reduction and blood pressure reduction. Orlistat and sibutramine...
Date:   May 2009
Title:   First-line drugs for hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   One of the most important decisions in treating people with elevated blood pressure is what drug class is used first. This decision has enormous consequences in terms of health outcomes and cost. In this review health outcomes resulting from 4 drug clas...
Date:   Apr 2009
Title:   Blood pressure lowering efficacy of diuretics as second-line therapy for primary hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Diuretics are a good first-line treatment for high blood pressure (BP). Diuretics include loop diuretics and thiazides. We asked how much do diuretics reduce BP when used as the second drug to treat hypertension. We performed a search of the available s...
Date:   Jan 2009
Title:   Endothelin receptor antagonists for pulmonary arterial hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Endothelin receptor antagonists have recently been proposed as an alternative to traditional therapies for pulmonary arterial hypertension. This updated review included eleven trials and 1457 participants in total. Endothelin receptor antagonists can im...
Date:   Dec 2008
Title:   Treatment blood pressure targets for hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   High blood pressure (BP) is linked to an increased risk of heart attack and stroke. High BP has been defined as any number larger than 140 to 160 /90 to 100 mmHg and as a result this range of BPs has become the standard blood pressure target for physici...
Date:   Oct 2008
Title:   Antihypertensive treatment for kidney transplant recipients
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In some patient groups, different blood pressure lowering drugs have differing relative beneficial and harmful effects in addition to their blood pressure lowering action. We investigated whether different classes of drugs might have different relative ...
Date:   Sep 2008
Title:   Blood pressure lowering efficacy of renin inhibitors for primary hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Elevated blood pressure or hypertension can lead to heart attacks and stroke. A new class of drugs called renin inhibitors are indicated for the treatment of hypertension. Aliskiren is a member of this new class and is the only one studied [or approved]...
Date:   Aug 2008
Title:   Balloon angioplasty versus medical therapy for hypertensive patients with renal artery obstruction
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Atherosclerosis can cause narrowing and hardening of the main blood vessel supplying the kidneys (renal artery stenosis) and resulting high blood pressure. Even using drugs that lower blood pressure (antihypertensives), atherosclerotic renal artery narr...
Date:   Jun 2008
Title:   Relaxation therapies for the management of primary hypertension in adults
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The World Health Organisation estimates that high blood pressure leads to over 7 million deaths each year, about 13% of the total deaths worldwide. If people lower their blood pressure, they are less likely to die or to have heart attacks and strokes. I...
Date:   Nov 2007
Title:   Bed rest with or without hospitalisation for hypertension during pregnancy
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Not enough evidence to say if bed rest in pregnancy helps women and their babies when women have high blood pressure....
Date:   Oct 2007
Title:   Pharmacological interventions for hypertensive emergencies
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Hypertensive emergencies occur when high blood pressure is associated with the presence of acute end organ damage, such as heart attack or stroke. There is controversy as to when and which blood pressure drugs to use in these situations. This review loo...
Date:   Oct 2007
Title:   Blood pressure lowering efficacy of angiotensin receptor blockers for primary hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   A class of drugs called angiotensin receptor blockers (ARBs) is commonly used to lower high blood pressure. This class includes drugs such as losartan (some brand names: Cozaar, Hyzaar), candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro, A...
Date:   Jul 2007
Title:   Blood pressure lowering efficacy of angiotensin converting enzyme (ACE) inhibitors for primary hypertension
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The class of drugs called ACE inhibitors is commonly used for the treatment of elevated blood pressure. This class includes drugs such as ramipril (brand name: Altace), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinzid...
Date:   Jul 2007
Title:   Sildenafil for pulmonary hypertension in neonates
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Some babies develop persistent pulmonary hypertension of the neonate (PPHN), a condition where the pressure in the blood vessel that allows blood to flow to the lungs remains abnormally high. Persistent high pressure in these vessels leads to less blood...
Date:   Apr 2007
Title:   Magnesium sulfate for persistent pulmonary hypertension of the newborn
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The blood pressure in the arteries of the lungs (pulmonary arteries) is normally much lower than the blood pressure in the rest of the body. Before a baby is born the muscle surrounding the pulmonary arteries is tightly constricted resulting in a very h...
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