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Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of treatments for managing high blood pressure.
Updated September 2008
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| Title: |
Blood pressure lowering efficacy of renin inhibitors for primary hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Elevated blood pressure or hypertension can lead to heart attacks and stroke. A new class of drugs called renin inhibitors are indicated for the treatment of hypertension. Aliskiren is a member of this new class and is the only one studied [or approved]...
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| Date: |
Aug 2008
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| Title: |
Prevention and treatment of postpartum hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
After birth, it is not uncommon for women to experience high blood pressure (hypertension), but it can have serious consequences. It can lead to stroke and, very rarely, death. It is unclear what causes hypertension after childbirth, or which women may...
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| Date: |
Nov 2004
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| Title: |
Pharmacotherapy for hypertension in women of different races
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Treating hypertension greatly reduces the risk of serious health problems such as heart disease or stroke in African American women and in older women. Hypertension (high blood pressure) is a risk factor for heart disease and stroke. Several treatments ...
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| Date: |
Dec 1999
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| Title: |
Sildenafil for pulmonary hypertension in neonates
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Some babies develop persistent pulmonary hypertension of the neonate (PPHN), a condition where the pressure in the blood vessel that allows blood to flow to the lungs remains abnormally high. Persistent high pressure in these vessels leads to less blood...
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| Date: |
Apr 2007
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| Title: |
Dieting to reduce body weight for controlling hypertension in adults
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Dieting to lose weight may lower blood pressure in overweight people with hypertension, but effects are modest and so dieting may not be effective alone.Hypertension (high blood pressure) predisposes people to heart disease and other serious health prob...
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| Date: |
Jul 1998
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| Title: |
Pharmacological interventions for hypertensive emergencies
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Hypertensive emergencies occur when high blood pressure is associated with the presence of acute end organ damage, such as heart attack or stroke. There is controversy as to when and which blood pressure drugs to use in these situations. This review loo...
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| Date: |
Oct 2007
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| Title: |
Antihypertensive drug therapy for mild to moderate hypertension during pregnancy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
During the early weeks of normal pregnancy, blood pressure falls and climbs slowly in later pregnancy to reach pre-pregnancy levels at term. Mild to moderate hypertension (high blood pressure) is common during pregnancy. In some women, it can become mor...
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| Date: |
Nov 2006
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| Title: |
Oral beta-blockers for mild to moderate hypertension during pregnancy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
While very high blood pressure (hypertension) in pregnancy can damage blood vessel walls and lead to serious complications, small rises in blood pressure may do little harm. The blood pressure level at which treatment should be started in pregnancy is n...
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| Date: |
Mar 2003
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| Title: |
Endothelin receptor antagonists for pulmonary arterial hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Endothelin receptor antagonists (ERAs), a class of potent vasodilators, have recently been proposed as an alternative to traditional therapies for pulmonary arterial hypertension. This updated review involved five trials and included 482 adults. The rev...
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| Date: |
May 2006
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| Title: |
Magnesium sulfate for persistent pulmonary hypertension of the newborn
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Persistent pulmonary hypertension of the newborn (PPHN) occurs in approximately 1.9 per 1000 newborns and may be more frequent in developing countries. Magnesium sulfate is a potent vasodilator and hence has the potential to reduce the high pulmonary arterial pressures associated with PPHN.
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| Title: |
Sildenafil for pulmonary hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Pulmonary hypertension (PH) is high blood pressure in the lung circulation. It can occur without a known cause, or it can be caused by another lung disease or be secondary to abnormalities in the left side of the heart. The review sought to determine wh...
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| Date: |
Aug 2004
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| Title: |
Treatment of hypertension in peripheral arterial disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
More research needed on the effects of medication to relieve high blood pressure in people with peripheral arterial disease. Atherosclerosis or hardening of the arteries is caused by deposits of fat, cholesterol and other substances building up plaque i...
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| Date: |
Jul 2003
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| Title: |
Beta-blockers for hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
At the present time members of the class of drugs called beta-blockers are commonly used as first-line treatment for elevated blood pressure. We asked whether this class of drugs was as good as other classes in preventing death, stroke and heart attacks...
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| Date: |
Oct 2006
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| Title: |
Blood pressure lowering efficacy of angiotensin receptor blockers for primary hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
A class of drugs called angiotensin receptor blockers (ARBs) is commonly used to assist in lowering elevated blood pressure (BP). This class includes drugs such as losartan, candesartan, eprosartan, irbesartan, telmisartan and valsartan. We asked how mu...
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| Date: |
Jul 2007
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| Title: |
Relaxation therapies for the management of primary hypertension in adults
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
The World Health Organisation estimates that high blood pressure leads to over 7 million deaths each year, about 13% of the total deaths worldwide. If people lower their blood pressure, they are less likely to die or to have heart attacks and strokes. I...
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| Date: |
Nov 2007
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| Title: |
Magnesium supplementation for the management of primary hypertension in adults
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review examined whether taking magnesium supplements could be recommended for treating adults with high blood pressure from no known cause. It reviewed 12 trials enrolling 545 people, which compared magnesium supplementation with a dummy drug (plac...
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| Date: |
Mar 2006
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| Title: |
Potassium supplementation for the management of primary hypertension in adults
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review examines whether taking potassium supplements can be recommended for treating adults with high blood pressure from no known cause. The results of the trials varied a lot: some trials found potassium lowered blood pressure much more than a du...
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| Date: |
Apr 2006
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