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Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of treatments for HIV and AIDS.
Reviewed September 2009
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| Title: |
Interventions for HIV-associated nephropathy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
HIV-associated nephropathy (HIVAN) is a kidney disease common among HIV positive patients, especially patients of African origin. The condition rapidly deteriorates if left untreated. Various treatment options exist, but the benefit of each is unknown. ...
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| Date: |
Jul 2009
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| Title: |
Deworming helminth co-infected individuals for delaying HIV disease progression
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Persons in resource-constrained settings are often disproportionately affected by both HIV-1 and other infectious diseases, such as helminth infections. Helminths are parasitic organisms that live within the human body. Over one-third of the world's pop...
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| Date: |
Jan 2009
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| Title: |
Iron supplementation for reducing morbidity and mortality in children with HIV
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Anaemia is one of the most common haematologic problem found in children with HIV/AIDS, second only to depletion of CD4/helper T lymphocytes. Anaemia in HIV-infected children can be caused by direct effects of HIV, other prevalent infections and opport...
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| Date: |
Sep 2008
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| Title: |
Therapeutic drug monitoring of antiretrovirals for people with HIV
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Monitoring the levels of HIV medications (antiretrovirals) in the blood of patients can reveal if levels are too high or too low. High levels may lead to side effects and low levels may not prevent the virus from multiplying. Prevention of virus replica...
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| Date: |
Jan 2008
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| Title: |
Antimotility agents for chronic diarrhoea in people with HIV/AIDS
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
People with HIV/AIDS often develop prolonged diarrhoea which are sometimes not caused by infections. This is more so in the sub-Saharan Africa where drugs for controlling HIV itself i.e. antiretroviral drugs (ARV) may not be widely available or affordab...
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| Date: |
Sep 2007
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| Title: |
Antiretroviral regimens for patients with HIV who fail first-line antiretroviral therapy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Highly active antiretroviral therapy has markedly reduced the morbidity and mortality of HIV-infected persons worldwide. There are many options for first-line ART, but second-line therapy is necessary for persons for fail the first-line treatment. This ...
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| Date: |
Aug 2007
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| Title: |
Megestrol acetate for treatment of anorexia-cachexia syndrome
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Megestrol acetate improves appetite and weight gain in patients with anorexia cachexia syndrome related to cancer.Megestrol acetate's mechanism of action is unknown. There are concerns regarding the possible recommendations for this drug; particularly i...
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| Date: |
Aug 2007
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| Title: |
Rifabutin for treating pulmonary tuberculosis
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Among current challenges in tuberculosis treatment are reducing the length of time that drugs must be taken to less than six months and find\ing ways to safely combine tuberculosis drugs with those used in the treatment of HIV infection. Rifabutin is a ...
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| Date: |
Jul 2007
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| Title: |
Nutritional interventions for reducing morbidity and mortality in people with HIV
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Achieving and maintaining optimal nutrition is considered an important adjunct in the clinical care of patients infected with HIV, as good nutrition can improve an individual's immune function, limit disease-specific complications, and improve quality o...
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| Date: |
May 2007
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| Title: |
Interventions for treating AIDS-associated Hodgkin's lymphoma in treatment-naive adults
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Lymphoma is a cancer of the lymphatic system. Lymphomas are classified into two general types: Hodgkin's disease and non-Hodgkin's lymphomas. Hodgkin's disease is the most common non-AIDS-defining malignancy in HIV-infected patients. Randomised controll...
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| Date: |
Feb 2007
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| Title: |
Interventions for squamous cell carcinoma of the conjunctiva in HIV-infected individuals
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review was conducted to evaluate the effects of the current interventions. No randomised controlled trials of any interventions for this cancer were found. Current clinical practice appears to be based on case series and case reports. These are wea...
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| Date: |
Feb 2007
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| Title: |
Adjunctive therapies for AIDS dementia complex
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
The authors did a systematic review of ten studies, to see if adjunctive therapies (supplemental to the main treatment) for AIDS dementia were effective and safe. They found no evidence that adjunctive therapies had any effect on the patients They did f...
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| Date: |
Feb 2007
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| Title: |
Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Millions of children worldwide acquire HIV/AIDS as a result of mother-to-child transmission (MTCT) during either pregnancy or breastfeeding. This is the primary means of infection for children under the age of 15 years. Researchers theorized that a cou...
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| Date: |
Nov 2006
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