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Follow the links below to find summaries of systematic reviews of the evidence of the effectiveness of treatments for epilepsy
Reviewed May 2008
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| Title: |
Specialist epilepsy nurses for treating epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. Problems in receiving epilepsy care include a lack of follow up, incorrect use and combination of drugs and poor communication between the perso...
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| Date: |
Jun 2001
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| Title: |
Oxcarbazepine add-on for drug-resistant partial epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. Oxcarbazepine is an antiepileptic drug which can be used as an add-on treatment for people with drug-resistant partial epilepsy who are resistan...
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| Date: |
Apr 2000
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| Title: |
Carbamazepine versus valproate monotherapy for epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Epilepsy is a disorder where recurrent seizures are caused by abnormal discharges from the brain. Carbamazepine is commonly used to treat partial seizures while valproate is used for generalized seizures. The review of trials found no evidence to suppor...
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| Date: |
Apr 2000
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| Title: |
Corticosteroids including ACTH for childhood epilepsy other than epileptic spasms
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Corticosteroids have been used in different forms and doses for various types of epilepsy in children. The review found no evidence for efficacy or safety of corticosteroids in the treatment of children with epilepsy. There is a need for larger, well-de...
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| Date: |
Nov 2006
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| Title: |
Epilepsy clinics versus general neurology or medical clinics
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. To assist people with epilepsy, specialist out-patient clinics have been suggested to ensure proper follow up, the correct use and combination o...
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| Date: |
Sep 2000
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| Title: |
Zonisamide add-on for drug-resistant partial epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
The majority of people with epilepsy have a good prognosis and their seizures can be well controlled with the use of a single antiepileptic agent, but up to 30% develop refractory epilepsy, especially those with partial seizures...
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| Date: |
Aug 2005
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| Title: |
Ketogenic diet for epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. Most seizures can be controlled by a single antiepileptic drug but sometimes seizures develop which are resistant to these drugs. The ketogenic ...
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| Date: |
Mar 2003
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| Title: |
Early versus late antiepileptic drug withdrawal for people with epilepsy in remission
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. Antiepileptic drugs (AEDs) are used to prevent these seizures but have long term adverse effects. When in remission, it may be best to stop usin...
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| Date: |
Mar 2001
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| Title: |
Remacemide for drug-resistant localization related epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. Most seizures can be controlled by a single antiepileptic drug but sometimes they are resistant to those drugs. The review of trials found that ...
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| Date: |
Jul 2002
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| Title: |
Non-pharmacological interventions for epilepsy in people with intellectual disabilities
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review identified the lack of any randomised controlled trials (RCTs) for non-pharmacological interventions in people with epilepsy and intellectual disabilities. There is evidently a need for well-designed RCTs to ascertain the effects of non-phar...
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| Date: |
Aug 2007
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| Title: |
Oxcarbazepine versus phenytoin monotherapy for epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. Most seizures can be controlled by a single antiepileptic drug. The review of trials found that the new drug, oxcarbazepine, used as a single tr...
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| Date: |
Feb 2006
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| Title: |
Self-management education for children with epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Self-management education may reduce the number of seizures, and improve other aspects of people's lives such as fear and knowledge about epilepsy....
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| Date: |
Feb 2007
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| Title: |
Self-management education for adults with epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Self-management education may reduce the number of seizures, and improve other aspects of people's lives such as fear and knowledge about epilepsy....
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| Date: |
Feb 2007
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| Title: |
Vigabatrin for refractory partial epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Vigabatrin taken with other antiepileptic drugs, as add-on therapy, can reduce seizures in people with drug-resistant partial epilepsy, although its use is associated with some side effects. These results were obtained from short-term randomised control...
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| Date: |
Jul 2008
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| Title: |
Lamotrigine add-on for drug-resistant partial epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Nearly a third of people with epilepsy continue to have seizures despite treatment with presently used (older) antiepileptic drugs (AEDs). The older AEDs also have adverse effects. As a result a range of new AEDs has been developed as 'add-on' treatment...
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| Date: |
May 2001
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| Title: |
Clobazam as an add-on in the management of refractory epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Only four randomised controlled trials have been undertaken assessing add-on clobazam for refractory epilepsy. All are cross-over studies of short duration; they used differing designs and were of poor methodological quality. Results suggest that clobaz...
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| Date: |
Feb 2008
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| Title: |
Therapeutic monitoring of antiepileptic drugs for epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
No evidence was found to indicate that the routine measurement of serum drug concentrations to inform drug dose adjustments is superior to drug dose adjustments made on clinical grounds alone in newly-diagnosed epilepsy patients treated with a single dr...
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| Date: |
Nov 2006
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| Title: |
Gabapentin add-on for drug-resistant partial epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. The review of trials found that a new antiepileptic drug, gabapentin is effective in the short-term when used with other drugs by people with dr...
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| Date: |
Oct 1998
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