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Follow the links below to find summaries of systematic reviews of the evidence of the effectiveness of treatments for epilepsy
Reviewed July 2009
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| Results 1 to 20 displayed. |
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| Title: |
Oxcarbazepine versus carbamazepine monotherapy for partial onset seizures
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Carbamazepine is the most commonly used drug to treat partial epileptic seizures. Oxcarbazepine is a newer drug that was developed with the intention to be as effective as carbamazepine but to cause fewer side effects. In this systematic review, we summ...
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| Date: |
Aug 2009
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| Title: |
Treatment of Lennox-Gastaut syndrome
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
The optimum treatment for Lennox-Gastaut syndrome has yet to be established. Lennox-Gastaut syndrome is a seizure (epilepsy) disorder which is commonly associated with behavioural and mental health problems. Many different treatments are currently used ...
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| Date: |
Apr 2009
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| Title: |
Vigabatrin for refractory partial epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Vigabatrin taken with other antiepileptic drugs, as add-on therapy, can reduce seizures in people with drug-resistant partial epilepsy, although its use is associated with some side effects. These results were obtained from short-term randomised control...
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| Date: |
May 2008
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| Title: |
Treatment of seizures in multiple sclerosis
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Epileptic seizures occur in a relatively small number of patients with multiple sclerosis, but can have serious consequences. Because the cause of epileptic seizures in patients in MS may be different from that in other forms of epilepsy, it is uncertai...
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| Date: |
Feb 2008
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| Title: |
Clobazam as an add-on in the management of refractory epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Only four randomised controlled trials have been undertaken assessing add-on clobazam for refractory epilepsy. All are cross-over studies of short duration; they used differing designs and were of poor methodological quality. Results suggest that clobaz...
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| Date: |
Feb 2008
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| Title: |
Tiagabine add-on for drug-resistant partial epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Tiagabine in combination with other antiepileptic drugs (add-on) can reduce seizures, but with some adverse effects....
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| Date: |
Feb 2008
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| Title: |
Zonisamide add-on for drug-resistant partial epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Zonisamide in combination with another antiepileptic drug can reduce seizures, but with some adverse effects....
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| Date: |
Feb 2008
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| Title: |
Traditional Chinese medicine for epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
There is no strong evidence for the use of traditional Chinese medicine as a treatment for epilepsy....
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| Date: |
Nov 2007
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| Title: |
Pregabalin add-on for drug-resistant partial epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Use of pregabalin in combination with other antiepileptic drugs can reduce the frequency of seizures, but has some adverse effects....
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| Date: |
Nov 2007
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| Title: |
Non-pharmacological interventions for epilepsy in people with intellectual disabilities
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review identified the lack of any randomised controlled trials (RCTs) for non-pharmacological interventions in people with epilepsy and intellectual disabilities. There is evidently a need for well-designed RCTs to ascertain the effects of non-phar...
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| Date: |
Aug 2007
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| Title: |
Carbamazepine versus phenytoin monotherapy for epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
There is no evidence to suggest any difference between the drugs carbamazepine and phenytoin for the seizure types studied....
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| Date: |
Jul 2007
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| Title: |
Carbamazepine versus valproate monotherapy for epilepsy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
No reliable evidence to distinguish between carbamazepine and valproate for partial onset seizures and generalized onset tonic-clonic seizures....
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| Date: |
Jul 2007
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| Title: |
Vagus nerve stimulation for partial seizures
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. Most seizures can be controlled by a single antiepileptic drug but sometimes seizures are drug-resistant. The review of trials found that vagus ...
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| Date: |
Jul 2007
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