Systematic Reviews of Treatments for Epilepsy
Follow the links below to find summaries of systematic reviews of the evidence of the effectiveness of treatments for epilepsy
Reviewed August 2011
49 Resources Found
| Title: | Eslicarbazepine acetate add-on for drug-resistant partial epilepsy |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Eslicarbazepine acetate is effective as a short-term add-on treatment for drug-resistant focal epilepsy. Epilepsy is a recurrent seizure disorder caused by abnormal electrical discharges from the brain. The majority of patients with epilepsy can contro... |
| Date: | Nov 2011 |
| Title: | Immediate-release versus controlled-release carbamazepine in the treatment of epilepsy |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Epilepsy is a common neurological disorder that is often treated with carbamazepine. With treatment, the number of seizures are often reduced but many people experience side effects. When carbamazepine is taken and it is absorbed into the body quickly t... |
| Date: | Aug 2011 |
| Title: | Calcium antagonists as an add-on therapy for drug-resistant epilepsy |
|---|---|
| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | No evidence to suggest that calcium antagonists have a useful effect on seizures. Nearly a third of people with epilepsy become resistant to antiepileptic drugs. These older drugs do not prevent seizures for everyone, and they have adverse effects. A ra... |
| Date: | Jul 2011 |
| Title: | Acupuncture for epilepsy |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Patients with epilepsy are currently treated with antiepileptic drugs, but a significant number of people continue to have seizures and many experience adverse effects to the drugs. As a result there is increasing interest in alternative therapies and a... |
| Date: | Jul 2011 |
| Title: | Clobazam as an add-on in the management of refractory epilepsy |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Only four randomised controlled trials have been undertaken assessing add-on clobazam for refractory epilepsy. All are cross-over studies of short duration; they used differing designs and were of poor methodological quality. Results suggest that clobaz... |
| Date: | Apr 2011 |
| Title: | Vigabatrin for refractory partial epilepsy |
|---|---|
| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Vigabatrin taken with other antiepileptic drugs, as add-on therapy, can reduce seizures in people with drug-resistant partial epilepsy although its use is associated with some side effects. These results were obtained from short-term randomised controll... |
| Date: | Mar 2011 |
| Title: | Psychological treatments for epilepsy |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | No reliable evidence supports psychological treatments for people with epilepsy. Psychological interventions are used in attempts to reduce seizure frequency, improve quality of life and avoid adverse effects of drugs among people with epilepsy. Of the ... |
| Date: | Feb 2011 |
| Title: | Non-pharmacological interventions for epilepsy in people with intellectual disabilities |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | This review identified the lack of any randomised controlled trials (RCTs) for non-pharmacological interventions in people with epilepsy and intellectual disabilities. There is evidently a need for well-designed RCTs to ascertain the effects of non-phar... |
| Date: | Feb 2011 |
| Title: | Pharmacological interventions for epilepsy in people with intellectual disabilities |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | This review confirms that in the majority of cases where intellectually disabled populations participated in trials of antiepileptic drugs (AEDs), moderate reductions in seizure frequency and occasional seizure freedom were obtained. Concern about side ... |
| Date: | Feb 2011 |
| Title: | Interventions for psychotic symptoms concomitant with epilepsy |
|---|---|
| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Little evidence to inform the treatment of psychosis in people with epilepsy. There is substantial evidence that people suffering from epilepsy have an increased risk of suffering from psychotic symptoms. These symptoms sometimes occur soon after or bef... |
| Date: | Feb 2011 |
| Title: | Intravenous immunoglobulins for epilepsy |
|---|---|
| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges in the brain. People with epilepsy may present with various types of immunological abnormalities. Most seizures can be controlled by antiepileptic drugs but som... |
| Date: | Dec 2010 |
| Title: | Felbamate as an add-on therapy for refractory epilepsy |
|---|---|
| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Only three randomized controlled trials have been found assessing add-on felbamate for refractory partial-onset epilepsy. They used differing designs. There is limited evidence to support the use of felbamate as an add-on treatment for refractory partia... |
| Date: | Dec 2010 |
| Title: | Strategies for improving adherence to antiepileptic drug treatment in patients with epilepsy |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | People with epilepsy can find it difficult to take their medicines as prescribed, and this is thought to be a reason for poor control of seizures. This review of trials reports interventions to improve patients' adherence to antiepileptic medications.... |
| Date: | Dec 2010 |
| Title: | Care delivery and self-management strategies for children with epilepsy |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Evidence for the best ways to care for children with epilepsy is still unclear. This review compared four education- or counselling-based interventions for children with epilepsy. One intervention was aimed solely at children, two were aimed at children... |
| Date: | Nov 2010 |
| Title: | Lamotrigine adjunctive therapy for refractory generalized tonic-clonic seizures |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | There is limited evidence that adjunctive lamotrigine reduces seizure frequency in patients with refractory primary generalized tonic-clonic seizures. |
| Date: | Sep 2010 |
| Title: | Tiagabine add-on for drug-resistant partial epilepsy |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Tiagabine in combination with other antiepileptic drugs (add-on) can reduce seizures, but with some adverse effects. Nearly a third of people with epilepsy become resistant to antiepileptic drugs (AEDs). Older AEDs do not prevent seizures for everyone a... |
| Date: | Sep 2010 |
| Title: | Vagus nerve stimulation for partial seizures |
|---|---|
| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Vagus nerve stimulator is a device that is effective as add-on treatment for drug-resistant partial epilepsy. Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. Most seizures can be controlled by... |
| Date: | Jun 2010 |
| Title: | Early versus late antiepileptic drug withdrawal for people with epilepsy in remission |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | There is not enough evidence to show the best time to withdraw antiepileptic drugs in adults with epilepsy who are free of seizures. More research is needed. Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges fr... |
| Date: | Mar 2010 |
| Title: | Therapeutic monitoring of antiepileptic drugs for epilepsy |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | No evidence to support routine therapeutic monitoring of antiepileptic drugs in the treatment of epilepsy. No evidence was found to indicate that the routine measurement of serum drug concentrations to inform drug dose adjustments is superior to drug do... |
| Date: | Feb 2010 |
| Title: | Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents |
|---|---|
| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Not enough evidence to show which drugs are best for treating seizures in children and adolescents with absence epilepsy Epilepsy is a disorder where seizures are caused by abnormal electrical discharges from the brain. Absence epilepsy involves seizure... |
| Date: | Feb 2010 |
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