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Systematic Reviews of Treatments for Cystic Fibrosis
Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of treatments for cystic fibrosis.
Reviewed August 2011
Related HealthInsite Topics
Systematic Reviews of Physiotherapy for Cystic Fibrosis
HealthInsite Topic Page
Links to systematic reviews of the evidence of the effectiveness of treating cystic fibrosis with physiotherapy.
52 Resources Found
| Title: | The use of drugs to manage symptoms in people with arthritis related to cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Arthritis is not a common complication of cystic fibrosis, but it can be a major complication when it does occur. There are two distinct types of arthritis in cystic fibrosis: cystic fibrosis-related arthropathy (CFA) and hypertrophic pulmonary osteoart... |
| Date: | Feb 2012 |
| Title: | Giving aminoglycoside antibiotics intravenously once daily compared to giving them several times per day in people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Cystic fibrosis is a serious genetic disorder which affects the lungs and the exocrine glands (sweat glands and others). Most people with cystic fibrosis develop persistent lung infections and they may receive frequent courses of intravenous antibiotics... |
| Date: | Jan 2012 |
| Title: | Palivizumab vaccine for prevention of respiratory syncytial virus infection in children with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Respiratory syncytial virus is a virus which commonly causes lung infections in infants and children. Although cases in most children are not severe, children with cystic fibrosis may be at higher risk for severe respiratory syncytial virus lung infecti... |
| Date: | Jan 2012 |
| Title: | The timing of inhalation of hypertonic saline in people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Inhalation of a strong, sterile, salt water solution (known as hypertonic saline) through a nebuliser improves the physical properties of sputum and stimulates cough in people with cystic fibrosis. Regular inhalation improves the clinical outcomes of pe... |
| Date: | Dec 2011 |
| Title: | A comparison of single and combined intravenous drug therapy for people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Cystic fibrosis is a serious genetic disease that affects cells in the exocrine glands (sweat glands and others). People with cystic fibrosis have a greater risk of chronic lung infections. They receive antibiotics by injection to treat these. The antib... |
| Date: | Nov 2011 |
| Title: | Antiviral treatment for influenza infection in people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Cystic fibrosis is a genetic, life-threatening disorder affecting multiple organs. People with cystic fibrosis have a higher risk of chronic lung disease. Influenza can worsen the course of the disease in cystic fibrosis by increasing the risk of pneumo... |
| Date: | Oct 2011 |
| Title: | Replacing the defective gene is a potential treatment for progressive lung disease in people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | In cystic fibrosis the gene encoding a protein called the cystic fibrosis transmembrane conductance regulator (CFTR) is faulty. People with cystic fibrosis suffer from progressive lung infection. This lung damage reduces life expectancy. Agents for CFTR... |
| Date: | Sep 2011 |
| Title: | Testing antibiotics in combination for acute infections of Pseudomonas aeruginosa in cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | The main cause of death in people with cystic fibrosis is due to chronic lung infection. People with cystic fibrosis now live longer due to the aggressive use of antibiotics to treat lung infections. Traditionally, antibiotics are chosen based on the re... |
| Date: | Sep 2011 |
| Title: | The training of muscles that cause the chest to expand in order to take air into the lungs for people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Cystic fibrosis is the most common life-limiting genetic condition in Caucasians. The life-expectancy of newly diagnosed patients is increasing. Inspiratory muscle training may improve quality of life, lung function and exercise tolerance in people with... |
| Date: | Sep 2011 |
| Title: | The use of regular vitamin D preparations for children and adults with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Cystic fibrosis with pancreatic insufficiency can cause vitamins, such as vitamin D, to be inadequately absorbed leading to vitamin deficiencies. Lack of vitamin D (vitamin D deficiency) can cause specific problems such as bone deformity and bone fractu... |
| Date: | Feb 2012 |
| Title: | The use of omega-3 supplements in people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Cycles of infection and inflammation are believed to worsen lung function in people with cystic fibrosis. Studies suggest that omega-3 fatty acids, such as those derived from fish oils, may be anti-inflammatory and may benefit many chronic inflammatory ... |
| Date: | Jul 2011 |
| Title: | Vaccines for preventing influenza in people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | People with cystic fibrosis have blocked airways which results in frequent airway infections. Infections with viral diseases like influenza ( |
| Date: | Jun 2011 |
| Title: | Use of oral steroids for cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Cystic fibrosis causes frequent lung infection and the airways become blocked with mucus. This in turn leads to inflammation, which causes more lung damage and more mucus to be produced. Corticosteroids are strong drugs given to treat this inflammation.... |
| Date: | Jun 2011 |
| Title: | Self-management education for cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | We set out to review the effects of self-management education for cystic fibrosis on a range of health outcomes in individuals of all ages with cystic fibrosis and their caregivers. Our search for available evidence identified four trials, and all four ... |
| Date: | Jun 2011 |
| Title: | Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Cystic fibrosis is a hereditary disease where thick mucus is produced in the lungs. Pseudomonas aeruginosa and other bacteria cause long-lasting lung infections which result in permanent lung damage. Vaccines aimed at reducing infection with Pseudomonas... |
| Date: | May 2011 |
| Title: | Steroids applied directly to polyps in the nose in people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | People with cystic fibrosis often have polyps in their nose which can cause discharge from the nose and block it up. We know that people with cystic fibrosis who have polyps in their nose also have more of some types of bacteria in their lungs. This can... |
| Date: | Apr 2011 |
| Title: | Inhaled drugs to open up the airways of people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | People with cystic fibrosis are often given drugs to open up their airways when they are breathless or wheezy. The drugs are given either by metered dose inhalers or nebulisers. We looked at how well these drugs worked in both children and adults. We in... |
| Date: | Apr 2011 |
| Title: | The timing of inhalation of dornase alfa in people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Inhaling the enzyme dornase alfa reduces the stickiness of sputum and improves clinical outcomes in people with cystic fibrosis. It is not certain whether it is better to inhale dornase alfa before or after clearing the airways with physical techniques.... |
| Date: | Apr 2011 |
| Title: | Non-invasive ventilation is the mechanical inflation and deflation of the lungs via a face mask which may help breathing during sleep, help reduce respiratory failure, help with clearance of sputum and help improve exercise tolerance. |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | As cystic fibrosis worsens, breathing can become difficult. This indicates the start of respiratory failure, where there is too much carbon dioxide and not enough oxygen in the blood. As respiratory failure progresses people may also have problems clear... |
| Date: | Mar 2011 |
| Title: | The use of oral drug therapy with agents other than steroids to reduce lung inflammation and deterioration in lung function in people with cystic fibrosis |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Inflammation contributes to lung damage. In the long term this is the most common reason for early death in cystic fibrosis. In high doses, non-steroidal anti-inflammatory drugs, particularly ibuprofen, may work against inflammation, but in low doses th... |
| Date: | Mar 2011 |
