Systematic Reviews of Treatments for Cystic Fibrosis

Follow the links below to find summaries of systematic reviews of the evidence for treatments for cystic fibrosis.

Reviewed January 2009

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43 Resources Found
Results 1 to 20 displayed.
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Title:   Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cystic fibrosis is a serious genetic disorder affecting cells in the exocrine glands (sweat glands and others). People with cystic fibrosis have a greater risk of chronic lung infections and intermittently receive courses of antibiotics by injection for...
Date:   Apr 2009
Title:   Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Excess mucus is produced in the lungs of people with cystic fibrosis. This leads to recurrent infection and tissue damage. It is important to clear this mucus using drugs and various chest physiotherapy techniques. We aimed to compare the effects of dif...
Date:   Feb 2009
Title:   Chest physiotherapy compared to no chest physiotherapy for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The lungs of people with cystic fibrosis produce excess mucus. This leads to repeated infection and tissue damage in the lungs. It is important to clear the mucus using drugs and chest physiotherapy (CPT). Physiotherapy clears mucus by various technique...
Date:   Feb 2009
Title:   Chemical pleurodesis versus surgical intervention for persistent and recurrent pneumothoraces in cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cystic fibrosis is an inherited disease which irreversibly damages the lungs. People with cystic fibrosis are prone to getting pneumothorax. A pneumothorax is defined as the presence of air in the space between the two linings of the lungs. It can poten...
Date:   Feb 2009
Title:   Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cystic fibrosis is a genetic disorder which mainly affects the lungs. Chest infections recur in people with cystic fibrosis due to a build up of thick sputum (phlegm) in the air passages. Several treatments, including thiol derivatives,aim to loosen th...
Date:   Jan 2009
Title:   Physical training for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The progress of lung disease in cystic fibrosis leads to abnormal breathing during exercise. This limits people exercising, which in turn affects health and body image. Physical training is designed to improve physical, heart and muscle strength through...
Date:   Jan 2009
Title:   Nebulised hypertonic saline for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   People with cystic fibrosis produce mucus in their lungs and airways (passages to the lungs) which is hard to clear. This leads to infections and damage to the airways. Chest physiotherapy or drugs (e.g. deoxyribonuclease) or both are used to try and cl...
Date:   Dec 2008
Title:   Oral non-steroidal anti-inflammatory drug therapy for lung disease in cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Inflammation contributes to lung damage, which, in the long term, is the most common reason for premature death in cystic fibrosis. In high doses, non-steroidal anti-inflammatory drugs, particularly ibuprofen, may work against inflammation, but in low d...
Date:   Nov 2008
Title:   Non-invasive ventilation for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   As cystic fibrosis (CF) worsens, breathing can become difficult. This indicates the start of respiratory failure where there is too much carbon dioxide and not enough oxygen in the blood. As respiratory failure progresses people may also have problems c...
Date:   Nov 2008
Title:   Newborn screening for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In people with cystic fibrosis lung disease and malnutrition occur very early in life. These complications are suited to early treatment. Newborn screening may therefore improve outcomes for people with cystic fibrosis. We aimed to find out whether newb...
Date:   Nov 2008
Title:   Topical cystic fibrosis transmembrane conductance regulator gene replacement for cystic fibrosis-related lung disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In cystic fibrosis (CF) the gene encoding a protein called the cystic fibrosis transmembrane conductance regulator (CFTR) is faulty. People with CF suffer from progressive lung infection. This lung damage reduces life expectancy. CFTR gene transfer agen...
Date:   Nov 2008
Title:   Single versus combination intravenous antibiotic therapy for people with cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cystic fibrosis is a serious genetic disease that affects cells in the exocrine glands (sweat glands and others). People with cystic fibrosis have a greater risk of chronic lung infections. They receive antibiotics by injection to treat these. The antib...
Date:   Nov 2008
Title:   Prophylactic anti-staphylococcal antibiotics for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cystic fibrosis blocks the airways with mucus and causes frequent respiratory infections, which may lead to death from breathing failure. People with cystic fibrosis are sometimes given antibiotics regularly in an attempt to prevent infections. However,...
Date:   Nov 2008
Title:   Ursodeoxycholic acid for cystic fibrosis-related liver disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Problems of bile composition and flow cause liver disease for up to 20% of young people with cystic fibrosis. Ursodeoxycholic acid is a naturally occurring bile acid given to try and prevent liver disease in cystic fibrosis. We searched for trials of th...
Date:   Nov 2008
Title:   Oral steroids for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cystic fibrosis causes frequent lung infection and the airways become blocked with mucus. This in turn leads to inflammation, which causes more lung damage and more mucus to be produced. Corticosteroids are strong drugs given to treat this inflammation....
Date:   Nov 2008
Title:   Oral calorie supplements for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cystic fibrosis affects many organs, including the digestive system. It can lead to food not being absorbed as it should be and so to growth problems. Children with cystic fibrosis need more energy than children without cystic fibrosis, but often have r...
Date:   Nov 2008
Title:   Oscillating devices for airway clearance in people with cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Excess mucus in the lungs of people with cystic fibrosis can lead to constant infection and inflammation. This damages the airways and results in a progressive loss in lung function. Chest physiotherapy attempts to clear excess mucus from the lungs of p...
Date:   Nov 2008
Title:   Oxygen therapy for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   People with cystic fibrosis (CF) suffer from breathing problems. Giving additional oxygen has long been a standard of care for people with chronic lung diseases. It is common for doctors to prescribe this treatment for people with CF when there is not e...
Date:   Nov 2008
Title:   Inhaled bronchodilators for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   People with cystic fibrosis are often given drugs to open up their airways when they are breathless or wheezy. The drugs are given either by metered dose inhalers or nebulisers. We looked at how well these drugs worked in both children and adults. We in...
Date:   Nov 2008
Title:   Inhaled corticosteroids for cystic fibrosis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Post-infection inflammation may contribute to lung damage; long term the most common cause of death in cystic fibrosis (CF). Corticosteroids treat inflammation but may cause adverse effects. These are more severe with oral corticosteroids, but may occur...
Date:   Nov 2008
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