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Follow the links below to find systematic reviews of the evidence for the effectiveness of treatments for breathing problems.
Created January 2008
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| Title: |
Lung protective ventilation strategy for the acute respiratory distress syndrome
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Critically ill patients affected by severe acute respiratory failure need air to be pumped into their lungs (mechanical ventilation) to survive. Mechanical support buys time for the lungs to heal. Nevertheless, 40 to 50% still die. Several studies sugge...
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| Date: |
Apr 2007
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| Title: |
Prophylactic methylxanthines for extubation in preterm infants
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Using methylxanthines to help wean babies from mechanical ventilation might help some babies. Methylxanthines are drugs (such as caffeine) that can help improve breathing in preterm babies (babies born early). They can be given to preterm babies when we...
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| Date: |
Apr 2008
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| Title: |
Nasal versus oral intubation for mechanical ventilation of newborn infants
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Babies in neonatal intensive care often need help to breathe, sometimes via a ventilator (machine). Air is mechanically pumped into their lungs through a tube that is either inserted into their mouth or nose (endotracheal intubation). Insertion can fail...
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| Date: |
Feb 1999
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| Title: |
Intravenous dexamethasone for extubation of newborn infants
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
The tube that is placed in the baby's airway to enable mechanical ventilation (machine-assisted breathing) can cause injury. This can lead to complications when the tube is removed (extubation). This review found that giving dexamethasone (a corticoster...
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| Date: |
Jul 2001
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| Title: |
Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Sickle cell disease is an inherited blood disorder. People with sickle cell disease often experience acute chest syndrome, although it is not known why. Acute chest syndrome can cause fever, coughing, chest pain, shortness of breath and pain, and can be...
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| Date: |
May 2003
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| Title: |
Anticholinergics for prolonged non-specific cough in children
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Children with non-specific cough, (non-productive cough in the absence of identifiable chest disease) are commonly treated with a variety of medications for control of cough symptoms. This review examined the effect of inhaled anti-cholinergic drugs in ...
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| Date: |
Mar 2008
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| Title: |
Nitric oxide for respiratory failure in infants born at or near term
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Inhaled nitric oxide can help some full term babies suffering respiratory failure who have not responded to the usual methods of support. Trials have shown that inhaled nitric oxide can increase the levels of oxygen in babies' blood and reduce the need ...
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| Date: |
May 2006
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| Title: |
Doxapram treatment for apnea in preterm infants
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Infant apnea is a pause in breathing of greater than 20 seconds. This can be harmful to the developing brain and cause dysfunction of the gastrointestinal tract or other organs. Drugs such as Doxapram are thought to stimulate breathing and are given to ...
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| Date: |
Jul 2004
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| Title: |
Digoxin for preventing or treating neonatal respiratory distress syndrome
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Sometimes a newborn baby has lungs that are not expanded properly. This is most common in preterm babies (born before 34 weeks) and is known as respiratory distress syndrome (RDS). Congestive heart failure may lead to fluid accumulation in the lungs, c...
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| Date: |
Jan 1998
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| Title: |
Symptomatic treatment of the cough in whooping cough
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Whooping cough (pertussis) is sometimes life-threatening. It is caused by a bacteria that usually affects babies and small children more severely. Immunisation can prevent it. Babies with whooping cough experience severe bouts of coughing, often leading...
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| Date: |
Aug 2003
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