Systematic Reviews of Treatments for Brain Injuries

Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of treatments for brain injuries.

Reviewed July 2009

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16 Resources Found
Results 1 to 16 displayed.

Title:   Modest cooling therapies (35C to 37.5C) for traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Traumatic brain injury (an injury to the brain that occurs as a result of a direct impact, such as may occur after road traffic accidents and falls) is a major cause of death and long-term disability worldwide.There is some evidence from animal experim...
Date:   Jul 2008

Title:   Decompressive craniectomy for the treatment of refractory high intracranial pressure in traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   An injury to the brain may cause it to swell. Pressure within the skull then increases as the brain has no room to expand; this excess pressure, known as intracranial pressure, can cause further brain injury. High intracranial pressure (ICP) is the most...
Date:   May 2008

Title:   Beta-2 receptor antagonists for acute traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Not all damage to the brain occurs at the moment of injury. The injury sustained at the moment of impact (primary brain injury) initiates a sequence of mechanisms which c...
Date:   Apr 2008

Title:   Interventions for apathy after traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Many people who have a traumatic brain injury experience apathy. Apathy is a decrease in cognitive, behavioural and emotional components of goal-directed activity due to reduced motivation. It is characterised by lessened activity, initiative and concer...
Date:   Jan 2008

Title:   Barbiturates for acute traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Severe head injury can lead to the brain swelling from blood leaking out or from clotting, or an imbalance in fluid around the brain. As space inside the skull is limited, this can cause dangerous levels of pressure on the brain (raised intracranial pre...
Date:   Jan 2008

Title:   Corticosteroids for acute traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Traumatic brain injury is a leading cause of death and disability. After the injury the brain may swell, causing a potentially fatal condition called raised intracranial pressure (ICP). Corticosteroid drugs have been widely used, for many years, to trea...
Date:   Jan 2008

Title:   Allopurinol for preventing mortality and morbidity in newborn infants with suspected hypoxic-ischaemic encephalopathy
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   There is insufficient evidence to determine whether giving allopurinol to newborn infants with suspected hypoxic-ischaemic encephalopathy and, therefore, is beneficial.Newborn infants who have been deprived of oxygen before, during, or after delivery (p...
Date:   Dec 2007

Title:   Psychological treatment for anxiety in people with traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Psychological interventions are commonly used in the management of anxiety and certain types of psychological treatments, such as cognitive behaviour therapy, are well suited to needs of individuals with traumatic brain injury (TBI). An advantage of the...
Date:   May 2007

Title:   Pharmacological management for agitation and aggression in people with acquired brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   This review found no firm evidence that drug management of agitation and aggression in adults with acquired brain injury is effective. There was weak evidence, based on a few small randomized controlled trials, that beta-blockers can improve aggression ...
Date:   Aug 2006

Title:   Hyperbaric oxygen therapy for the adjunctive treatment of traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Traumatic brain injury is a major cause of death and disability. Not all damage to the brain occurs at the moment of injury; reduction of the blood flow and oxygen supply to the brain can occur afterwards and cause further secondary brain damage, which ...
Date:   Apr 2006

Title:   Mannitol for acute traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Mannitol is a sugar alcohol solution which is sometimes effective in reducing brain swelling after head injury. However, its effectiveness in the ongoing treatment of severe head injury remains unclear. There is evidence that excessive administration of...
Date:   Mar 2006

Title:   Calcium channel blockers for acute traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Acute traumatic brain injury is a major cause of death and disability. Not all damage to the brain occurs at the moment of injury; reduction of blood flow and oxygen supply to the brain can occur afterwards and cause further brain damage, which is an im...
Date:   Nov 2005

Title:   Monoaminergic agonists for acute traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Not all of the brain damage sustained after a traumatic brain injury (TBI) is due to the direct injury that occurs at the moment of impact. Severe injury can initiate a sequence of events over several hours that can lead to secondary damage or death of ...
Date:   May 2005

Title:   Fluid restriction for term infants with hypoxic-ischaemic encephalopathy following perinatal asphyxia
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Plain language summary will be included with future review update....

Title:   Excitatory amino acid inhibitors for traumatic brain injury
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Brain injury can start a cascade of damage to brain tissue. Release into the brain of excess excitatory amino acids is thought to begin this process. Drugs which stop the release of excitatory amino acids or which block them may reduce brain damage. Stu...
Date:   Nov 2002

Title:   Sensory stimulation for brain injured individuals in coma or vegetative state
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   About half of people in a coma (deep unconsciousness) because of traumatic brain injury will wake within a year of the accident. Speeding recovery to allow people to wake sooner is a priority for them and their family. One type of treatment uses sensory...
Date:   Feb 2002
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