Systematic Reviews of Treatments for Brain Cancer

Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of treatments for brain cancer and brain tumours.
Reviewed December 2011

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12 Resources Found

Results 1 to 12 displayed.

Title:   Whole brain radiotherapy for the treatment of multiple brain metastases
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Radiotherapy is commonly used to treat patients with cancer that has spread to the brain. The aim of this review was to determine the effectiveness and adverse effects of whole brain radiotherapy (WBRT) alone or in combination with other treatments in a...
Date:   Mar 2012
Title:   Antiepileptic drugs for treating seizures in adults with brain tumours
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Seizures are a common symptom of both primary and secondary brain tumours and can cause significant morbidity. The mainstay of treatment for seizures in adults with brain tumours is medical therapy with antiepileptic drugs. This review appraises the evi...
Date:   Jul 2011
Title:   Surgery and whole brain radiation therapy versus whole brain radiation therapy alone for single brain metastases
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   For patients with single brain metastasis there is good evidence from randomised controlled trials (RCTs) that surgery in addition to whole brain radiation therapy (WBRT) does not improve overall survival.Treatment of brain metastasis is usually palliat...
Date:   Feb 2011
Title:   Biopsy versus resection for high grade glioma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Malignant gliomas are aggressive tumours of the nervous system. Resection (surgery to remove the tumour) may relieve symptoms but there is uncertainty that it extends survival. Biopsy can confirm diagnosis and carries fewer risks, but will not extend su...
Date:   Feb 2011
Title:   Treatment of high grade glioma with anti-cancer drug (chemotherapy) coated implants
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   High grade glioma is a rapidly progressive form of brain tumour. Standard therapy involves the use of surgery (either biopsy or resection) and radiotherapy plus or minus temozolomide. Chemotherapy was not previously used due to concerns over efficacy an...
Date:   Feb 2011
Title:   Pharmacological treatment of depression in patients with a primary brain tumour
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   People with brain tumours may experience epilepsy, memory problems and fatigue. Depression is also common and doctors might choose to treat this with antidepressants, since antidepressants are thought to be effective in other patients. However, antidepr...
Date:   Feb 2010
Title:   Is adding focused radiation (radiosurgery) to whole brain radiation therapy (WBRT) beneficial to patients with brain metastases?
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   We identified three RCTs that looked at whether adding focused radiation (radiosurgery) to whole brain radiation therapy (WBRT) is beneficial to patients with brain metastases. Most of our conclusions are based on the results of one large trial with unc...
Date:   Nov 2009
Title:   Surgery or radiosurgery for solitary brain metastases from non-small cell lung cancer
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   A solitary brain metastasis is the spread of cancer to the brain some time after successful treatment of the primary cancer. When the metastasis is caused by non-small cell lung cancer there are two main treatment options: surgery and radiosurgery. Radi...
Date:   Jul 2009
Title:   Antiepileptic drugs for preventing seizures in people with brain tumors
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Up to 60% of people with brain tumors may present with seizures, or may have a seizure for the first time after diagnosis or neurosurgery. The risk of a seizure varies with the tumor type and its location in the brain. Seizures are an added burden with ...
Date:   Feb 2008
Title:   Anaplastic oligodendrogliomas (AO) and anaplastic oligoastrocytomas (AOA) are relatively rare brain tumors. They have been traditionally treated with surgery followed by radiotherapy
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Two randomized controlled trials (RCTs) have found that, although the addition of procarbazine, lomustine, and vincristine (PCV) chemotherapy to standard treatment does not prolong survival, it does delay progression of these tumors. However, this chemo...
Date:   Feb 2008
Title:   Prophylactic cranial irradiation improves survival rate of patients with small-cell lung cancer in complete remission
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Small-cell lung cancer accounts for 20-25% of lung cancer. Treatment with chemotherapy and thoracic radiotherapy yields complete response rates of 50-85%. But, due to relapses, only 15% of patients who achieved complete response survived at 3 years sinc...
Date:   Nov 2003
Title:   Including chemotherapy in the treatment of high-grade glioma improves survival
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   High-grade glioma is a brain tumour that is difficult to treat successfully. Standard treatment is by surgery to reduce the tumour size, followed by radiotherapy. Adding chemotherapy to the treatment results in a small but significant prolongation of su...
Date:   Aug 2003

Results 1 to 12 displayed.