Systematic Reviews of Treatments for Asthma in Children and Young People

Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of treatments for asthma in children and young people.

Created May 2007

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23 Resources Found
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Title:   Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The aim of this review was to compare the response to inhaled beta-2 agonists delivered through metered-dose inhaler (MDI) attached to home-made spacers, to beta-2 agonists delivered through MDI attached to commercially produced spacers, in children wit...
Date:   Jan 2008
Title:   Herbal interventions for chronic asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Herbal interventions for chronic asthma in asthma and childrenChronic asthma is a inflammatory disease of the airways characterised by wheeze and breathlessness. Drug therapy is usually used to control symptoms but complementary medicine is often used, ...
Date:   Nov 2007
Title:   Nedocromil sodium for chronic asthma in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Nedocromil (or Tilade) is a 'preventer' therapy used to treat chronic asthma in children. It is thought to be safer than inhaled steroids and can be used for the management of mild to moderate asthma. The review of studies including 15 trials and 1422 c...
Date:   Apr 2006
Title:   Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Inhaled corticosteroids (ICS) and sodium cromoglycate (SCG) have been advocated as medications to control persistent asthma symptoms among children and adults, yet information on which class of drugs is superior has been conflicting. This study pooled r...
Date:   Feb 2006
Title:   Oral xanthines as maintenance treatment for asthma in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Xanthines (e.g. theophylline) are a group of drugs thought to have helpful preventative and reliever properties in the treatment of asthma in children. This review of studies has established that there is evidence for useful effects of these drugs in te...
Date:   Nov 2005
Title:   Fluticasone versus placebo for chronic asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Fluticasone is a well-established inhaled steroid for use a preventative agent in controlling asthma symptoms. This review found that it is highly effective even in low doses. The effect does appear to increase with higher doses, but these improvements ...
Date:   Jun 2005
Title:   Anticholinergic drugs for wheeze in children under the age of two years
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Anti-cholinergic drugs are widely used to treat infants and young toddlers with acute and recurrent wheeze though the role of these agents remain controversial. Six trials involving 321 infants in three different settings were reviewed. The review was u...
Date:   Apr 2005
Title:   Fluticasone at different doses for chronic asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Fluticasone (FP) is an inhaled corticosteroid commonly used to treat inflammation of the airways (passages to the lungs) and improve breathing in people with asthma. This review examined the effectiveness of FP when given at different doses for treating...
Date:   Apr 2005
Title:   Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Acute asthma is a common paediatric emergency prevalent in many countries. Treatment aims to reverse asthma by opening up the airways and targeting the underlying inflammation of the airways. Beta-agonists, anticholinergic agents and glucocorticoids are...
Date:   Jan 2005
Title:   Beclomethasone versus placebo for chronic asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   During an asthma attack, the airways narrow, causing breathing problems, wheezing and coughing. Inhaled corticosteroids (ICS) are used to reduce swelling of the airways. Inhaled beclomethasone dipropionate (BDP) is commonly used. There is now a new form...
Date:   Oct 2004
Title:   Psychological interventions for children with asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   It is thought that psychological factors may play an important part in asthma, although this could not be determined in a previous review of psychological interventions in adults with asthma. Although there were twelve studies in this review that met in...
Date:   Sep 2004
Title:   Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Children with asthma can find using inhaled treatments medication difficult and so oral medication such as ketotifen, which is an antihistamine, can be used to help control symptoms. The review found that mild asthma symptoms were well-controlled in the...
Date:   Nov 2003
Title:   Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In an asthma attack, the airways (passages to the lungs) narrow from muscle spasms and swelling (inflammation), which can cause breathing problems, wheezing and coughing. Inhaled corticosteroid drugs are used to reduce the swelling of the airways in pe...
Date:   Oct 2003
Title:   High dose versus low dose inhaled corticosteroid as initial starting dose for asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   People with asthma should start their treatment with low to moderate doses of ICS....
Date:   Aug 2003
Title:   Sodium cromoglycate for asthma in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In this review we aimed to determine whether there is evidence for the effectiveness of inhaled sodium cromoglycate as maintenance treatment in children with chronic asthma. Most of the studies were carried out in small groups of patients. Furthermore, ...
Date:   May 2003
Title:   Corticosteroids for hospitalised children with acute asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   An acute asthma attack in a child often results in a trip to the hospital. In the emergency department steroid drugs are given which may improve the child's condition and allow them to be sent home after a few hours observation. However, some children ...
Date:   Oct 2002
Title:   Anticholinergic therapy for chronic asthma in children over two years of age
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Anticholinergic drugs are widely used in the management of both acute and chronic asthma in children. Their effect is achieved through relief of narrowing of the airways that occurs in asthma. Current guidelines for the management of chronic asthma advi...
Date:   Sep 2002
Title:   Oxatomide for stable asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Oxatomide, an anti-histamine agent, cannot be recommended for the treatment of chronic asthma as there is no consistent data to support a beneficial effect on asthma control. Six randomised controlled studies of the effect of oxatomide were identified. ...
Date:   Aug 2002
Title:   Combined inhaled anticholinergics and beta2-agonists for initial treatment of acute asthma in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In an asthma attack, the airways (passages to the lungs) narrow from muscle spasms. Bronchodilators (reliever inhalers) relax the muscles in the airways, opening the airways so breathing is easier. Anti-cholinergic drugs can also affect these muscles, a...
Date:   Apr 2000
Title:   Family therapy for asthma in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Psychological factors may have an effect on asthma in children, or its severity. As some children with families who are having problems have severe asthma, family therapy has been tried. The aim is to resolve any problems there might be in a family, in ...
Date:   Sep 1999
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