Systematic Reviews of Transplantation Procedures

Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of transplantation procedures - including bone marrow, heart, kidney, liver and stem cell transplants, and also xenotransplantation (animal to human).
Reviewed April 2012

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37 Resources Found

Results 1 to 20 displayed.     1  2 

Title:   Calcineurin inhibitor minimisation, ie, reduction or withdrawal, versus continuation of calcineurin inhibitor treatment for liver transplant patients
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Almost every liver transplant recipient is treated with either the drug tacrolimus or the drug cyclosporine to prevent rejection of the transplanted liver. These drugs are part of a group of drugs called calcineurin inhibitors. Both tacrolimus and cyclo...
Date:   Jan 2012
Title:   Methods to decrease blood loss and transfusion requirements for liver transplantation
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The liver is the powerhouse of the body. It acts as a store of energy and a centre of metabolic activity. Liver transplantation is the main treatment for severe liver disease resulting in destruction of the liver (which can happen suddenly or over a per...
Date:   Sep 2011
Title:   Prostaglandins for liver transplanted patients
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Liver transplantation is the most effective treatment for patients with advanced liver disease (cirrhosis). However, early postoperative problems such as graft failure or acute renal failure requiring dialysis are common. Patients evolving with such pro...
Date:   Aug 2011
Title:   Transplantation of blood-forming stem cells for people with ß-thalassaemia major
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Thalassaemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form of haemoglobin (the protein in red blood cells that carries oxygen). The disorder results in excessive destruction of red blood cells, wh...
Date:   Aug 2011
Title:   Stem cell treatment following a heart attack
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Currently the standard treatment for people suffering a heart attack (due to a blockage in the artery supplying blood to the heart) is to directly open the artery with a tiny balloon in a procedure called primary angioplasty and to introduce a small tub...
Date:   Jul 2011
Title:   Routine drainage for orthotopic liver transplantation
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Surgeons insert a drain (a tube emerging from the tummy to the exterior) with an intention of detecting, monitoring, or prevention of any blood or body fluids collection in the abdominal cavity after the operation. This is called abdominal drain. While ...
Date:   Mar 2011
Title:   Endothelial keratoplasty versus penetrating keratoplasty for Fuchs endothelial dystrophy
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The human cornea is the clear window at the front of the eye. It is made of five layers. The inner-most layer is the endothelial cell layer and it is essential for maintaining corneal transparency. It does this by pumping any fluid out of the cornea thu...
Date:   Feb 2011
Title:   Hematopoietic stem cell transplantation following chemotherapy for non-rhabdomyosarcoma soft tissue sarcomas
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Non-rhabdomyosarcoma soft tissue sarcomas are a group of rare cancers. Patients with inoperable or metastatic disease have a poor prognosis. It was believed higher doses of chemotherapy might improve patients' survival. However, high doses of chemothera...
Date:   Jan 2011
Title:   Is routine veno-venous bypass necessary in liver transplantation?
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   During liver transplantation major veins are clamped (blocked using clamps) by the surgeon in order to complete the operation. This can decrease the blood returning to the heart which has the potential to decrease the blood pressure and the blood flow t...
Date:   Dec 2010
Title:   Treatment of reduced blood flow to the legs using mononuclear cell therapy
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Critical limb ischaemia (CLI) occurs when blood flow to the legs is reduced because of the worsening of peripheral arterial disease. Initially, patients experience cramping leg pain that limits walking (termed intermittent claudication), but over time s...
Date:   Nov 2010
Title:   Piggy-back method versus standard method of liver transplantation
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   During liver transplantation, the major vein to the heart (inferior vena cava (IVC)) is clamped (blocked by using clamps) by the surgeon in order to complete the operation. This allows a section of IVC to be removed along with the diseased liver. Howeve...
Date:   Nov 2010
Title:   High dose chemotherapy and autologous bone marrow or stem cell transplantation versus conventional chemotherapy for women with metastatic breast cancer
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Advanced or 'metastatic' breast cancer is cancer that has spread beyond the breast and underarm lymph nodes to other parts of the body. Although metastatic breast cancer is often responsive to conventional chemotherapy it does not provide a cure. The do...
Date:   Oct 2010
Title:   Transplantation of blood-forming stem cells for children with sickle cell disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Sickle cell disease is a genetic disorder mainly characterized by the presence of deformed, sickle-shaped red blood cells in the blood stream. These cells deprive tissues of blood and oxygen resulting in periodic and recurrent painful attacks. Complicat...
Date:   Oct 2010
Title:   No evidence to support use of preventive antiviral drugs in patients undergoing liver transplantation for hepatitis C viral infection
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   It is not clear whether antiviral therapy is indicated in patients undergoing liver transplantation for chronic liver disease incompatible with long-term survival resulting from hepatitis C virus (HCV) infection. We performed a Cochrane review of random...
Date:   Aug 2010
Title:   High-dose chemotherapy with autologous stem cell transplantation in the first line treatment of aggressive Non-Hodgkin Lymphoma (NHL) in adults
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Aggressive Non-Hodgkin's Lymphomas (NHLs) are fast growing forms of lymphoma. The most common type is a diffuse large B-Cell lymphoma (DLCL) but there are several other subtypes of aggressive lymphoma and variants of DLCL, such as centroblastic, immunob...
Date:   Jun 2010
Title:   Stem cell transplantation for treating Gaucher disease
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Gaucher disease is an inherited disorder caused by a deficiency of the enzyme glucocerebrosidase. This leads to storage of complex lipids in some types of blood cells. Due to these abnormal cells people with Gaucher disease will have pain, fatigue, anem...
Date:   Jun 2010
Title:   Stem cell transplantation for ischemic stroke
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Once stroke-induced cell damage has occurred, little can be done to improve functional outcome. Stem cell transplantation has been shown to be safe and effective in ischemic stroke animal models but evidence in patients is still lacking. This review fou...
Date:   Mar 2010
Title:   Bile acids for liver-transplanted patients
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Liver transplantation is a major surgical procedure that has been practiced for more than forty years and has nowadays become a generally accepted treatment option in patients with end-stage liver disease. The most common cause for liver transplantation...
Date:   Feb 2010
Title:   Choice of bypass graft material for lower limb arterial bypasses
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   A person with severely diseased arteries in the leg(s), can experience pain on walking only short distances (critical claudication), pain at rest, or death of tissues in the leg. When the main thigh artery has a long blockage, the best option is to inse...
Date:   Jan 2010
Title:   Patches of different types for carotid patch angioplasty
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   About 20% of strokes result from narrowing of the carotid artery (the main artery supplying blood to the brain). Carotid endarterectomy is an operation that involves opening the carotid artery to remove this narrowing and therefore reduce the risk of st...
Date:   Nov 2009

Results 1 to 20 displayed.     1  2