Systematic Reviews of Asthma Medicines

Follow the links below to find systematic reviews of the evidence for the effectiveness of asthma medications.

Updated Februuary 2009

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Systematic Reviews on Complications of Asthma Medications
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Links to systematic reviews of the evidence for the possible health complications of medications for asthma.

44 Resources Found
Results 1 to 20 displayed.
1    2    3   

Title:   Leukotriene receptor antagonists for non-cystic fibrosis bronchiectasis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Leukotriene receptor antagonists are a new class of drug which may have an anti-inflammatory action in some patients with asthma. In theory they may also be of benefit in bronchiectasis, but no randomised controlled trials have yet been reported so it i...
Date:   Apr 2009

Title:   Inhaled sodium cromoglycate for asthma in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In this review we aimed to determine whether there is evidence for the effectiveness of inhaled sodium cromoglycate as maintenance treatment in children with chronic asthma. Most of the studies were carried out in small groups of patients. Furthermore, ...
Date:   Feb 2009

Title:   Anticholinergic therapy for chronic asthma in children over two years of age
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Anticholinergic drugs are widely used in the management of both acute and chronic asthma in children. Their effect is achieved through relief of narrowing of the airways that occurs in asthma. Current guidelines for the management of chronic asthma advi...
Date:   Feb 2009

Title:   Continuous versus intermittent beta-agonists for acute asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   During acute asthma attacks, inhaled beta-agonists (reliever medications) are used to treat spasm in the airways in the lungs. The medication can be administered by wet nebulisation or from an inhaler with a holding chamber; wet nebulisation may be deli...
Date:   Feb 2009

Title:   Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Pharmacological treatment of asthma is tailored based on various subjective or objective outcome measures. The objective of this review was to evaluate the efficacy of tailoring asthma interventions based on sputum eosinophils in comparison to clinical ...
Date:   Dec 2008

Title:   Regular treatment with formoterol and inhaled steroids for chronic asthma: serious adverse events
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   There has been some concern raised at the possibility of increased serious adverse events following administration of formoterol, a long-acting beta-agonist, to people with asthma. We analysed data from 14 studies in adults and seven in children. Too fe...
Date:   Nov 2008

Title:   Nedocromil sodium for chronic asthma in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Nedocromil (or Tilade) is a 'preventer' therapy used to treat chronic asthma in children. It is thought to be safer than inhaled steroids and can be used for the management of mild to moderate asthma. The review of studies including 15 trials and 1422 c...
Date:   Nov 2008

Title:   Vitamin C supplementation for asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Asthma is a chronic inflammatory disease of the airways characterised by wheeze and breathlessness. One theory for the observed increase in the number of people with asthma is the 'western' diet with it's lack of nutrients from fresh food. We reviewed e...
Date:   Oct 2008

Title:   Nedocromil sodium for preventing exercise-induced bronchoconstriction
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Exercise-induced asthma can limit people's endurance, prolong recovery time after exercise, and lead to people avoiding exercise. The episode involves symptoms such as coughing, wheezing, shortness of breath and chest tightness. The review of trials fou...
Date:   Aug 2008

Title:   Inhaled versus oral steroids for adults with chronic asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Inhaled corticosteroids form the first choice for preventative treatment of asthma, but they remain expensive for health economies in developing countries. Oral prednisolone is very much cheaper. In this review, we found that, in the management of adult...
Date:   Aug 2008

Title:   Inhaled beta2-agonists for asthma in mechanically ventilated patients
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   During an asthma attack, the airways narrow, causing breathing problems, wheezing and coughing. A small number of people with asthma need medications given by tubes during mechanically assisted breathing (ventilated). Inhaled bronchodilators help reliev...
Date:   Aug 2008

Title:   Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In acute asthma attacks higher doses of inhaled Ö2-agonists (reliever inhalers) are used to overcome the narrowing of the passages in the lungs. The medication can be given by wet nebulisation or from an inhaler with a spacer device (holding chamber). Th...
Date:   Jul 2008

Title:   Holding chambers versus nebulisers for inhaled steroids in chronic asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In an asthma attack, the airways (passages to the lungs) narrow from muscle spasms, and from swelling (inflammation). Inhaling corticosteroid drugs can relieve this swelling, and so ease asthma. These drugs have usually been inhaled through inhalers wit...
Date:   Jul 2008

Title:   Anticholinergic drugs for wheeze in children under the age of two years
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Anti-cholinergic drugs are widely used to treat infants and young toddlers with acute and recurrent wheeze though the role of these agents remain controversial. Six trials involving 321 infants in three different settings were reviewed. The review was u...
Date:   Jun 2008

Title:   Combination formoterol and inhaled steroid versus beta2-agonist as relief medication for chronic asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Combined formoterol and budesonide inhalers can be used for maintenance treatment of asthma and relief of symptoms. Three trials involving 5905 participants were included. We found very little evidence in relation to the use of formoterol and budesonide...
Date:   Apr 2008

Title:   Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In this review involving 356 subjects, we found that tailoring the dose of inhaled corticosteroids based on exhaled nitric oxide (compared to clinical symptoms with or without spirometry/peak flow) was beneficial in reducing the final (but not the overa...
Date:   Jan 2008

Title:   Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The aim of this review was to compare the response to inhaled beta-2 agonists delivered through a metered-dose inhaler (MDI) attached to home-made spacers, compared with beta-2 agonists delivered through a MDI attached to commercially produced spacers i...
Date:   Jan 2008

Title:   Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Children with asthma can find using inhaled treatments medication difficult and so oral medication such as ketotifen, which is an antihistamine, can be used to help control symptoms. The review found that mild asthma symptoms were well-controlled in the...
Date:   May 2007

Title:   Macrolides for chronic asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Asthma is a chronic inflammatory disorder of the airways. Macrolide antibiotics are potential antiinflammatory drugs that may be of use in asthma. This systematic review examined several randomised controlled trials of macrolide antibiotic therapy in as...
Date:   May 2007

Title:   Corticosteroids for preventing relapse following acute exacerbations of asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In an asthma attack, the airways (passages to the lungs) narrow from muscle spasms and swelling (inflammation). Bronchodilators (reliever inhalers to open up the lungs and airways) can be used for the spasms, and corticosteroids for the swelling. Howeve...
Date:   Apr 2007
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