Systematic Reviews of Asthma Medicines

Follow the links below to find systematic reviews of the evidence for the effectiveness of asthma medications.

Created January 2008

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63 Resources Found
Results 1 to 20 displayed.
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Title:   Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In this review involving 356 subjects, we found that tailoring the dose of inhaled corticosteroids based on exhaled nitric oxide (compared to clinical symptoms with or without spirometry/peak flow) was beneficial in reducing the final (but not the overa...
Date:   Jan 2008
Title:   Corticosteroids for hospitalised children with acute asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   An acute asthma attack in a child often results in a trip to the hospital. In the emergency department steroid drugs are given which may improve the child's condition and allow them to be sent home after a few hours observation. However, some children ...
Date:   Oct 2002
Title:   Oxatomide for stable asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Oxatomide, an anti-histamine agent, cannot be recommended for the treatment of chronic asthma as there is no consistent data to support a beneficial effect on asthma control. Six randomised controlled studies of the effect of oxatomide were identified. ...
Date:   Aug 2002
Title:   Budesonide versus placebo for chronic asthma in children and adults
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Budesonide is highly effective preventative treatment for all patients with asthma, irrespective of age or severity of their disease. Most benefits are seen with low-moderate doses....
Date:   Jun 1999
Title:   Antibiotics for acute asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Patients with acute asthma who require admission to hospital are often treated with antibiotics, in case the underlying cause of the attack is a bacterial infection. This review examines the evidence regarding this therapy and whether it is justified in...
Date:   Dec 2000
Title:   Pressurised metered dose inhalers versus all other hand-held inhaler devices to deliver beta-2 agonist bronchodilators for non-acute asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   A number of different inhaler devices are available to deliver beta2-agonist bronchodilators in asthma. These include hydrofluoroalkane (HFA) or chlorofluorocarbon (CFC)-free propelled pressurised metered dose inhalers (pMDIs) and dry powder devices.
Title:   Nedocromil sodium versus sodium cromoglycate for preventing exercise-induced bronchoconstriction
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Exercise-induced asthma can limit people's endurance, prolong recovery time after exercise, and lead to people avoiding exercise. The episode involves symptoms such as coughing, wheezing, shortness of breath and chest tightness. Two drugs, nedocromil so...
Date:   Mar 2000
Title:   Fluticasone versus placebo for chronic asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Fluticasone is a well-established inhaled steroid for use a preventative agent in controlling asthma symptoms. This review found that it is highly effective even in low doses. The effect does appear to increase with higher doses, but these improvements ...
Date:   Jun 2005
Title:   Sodium cromoglycate for asthma in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In this review we aimed to determine whether there is evidence for the effectiveness of inhaled sodium cromoglycate as maintenance treatment in children with chronic asthma. Most of the studies were carried out in small groups of patients. Furthermore, ...
Date:   May 2003
Title:   Inhaled steroids for episodic viral wheeze of childhood
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   A wheeze that is recurrent and caused by a viral upper respiratory tract infection (URTI) is different to asthma. Episodic recurrent wheezing happens in children who have no symptoms in between episodes and is different to wheezing that is persistent. C...
Date:   Oct 1999
Title:   Combined inhaled anticholinergics and beta2-agonists for initial treatment of acute asthma in children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   In an asthma attack, the airways (passages to the lungs) narrow from muscle spasms. Bronchodilators (reliever inhalers) relax the muscles in the airways, opening the airways so breathing is easier. Anti-cholinergic drugs can also affect these muscles, a...
Date:   Apr 2000
Title:   Regular treatment with long acting beta agonists versus daily regular treatment with short acting beta agonists in adults and children with stable asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Patients with chronic asthma are generally treated with a 'preventer medication' to reduce the underlying airways inflammation but often require bronchodilators for their symptoms. Treatment with regular long acting Beta-agonist bronchodilator agents, s...
Date:   Apr 2002
Title:   Chloroquine as a steroid sparing agent for asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Asthma can be treated with drugs which aim to reduce inflammation in the airways. Inhaled corticosteroids are frequently used, but occasionally individuals require oral steroids for adequate control. However, oral steroids are frequently associated with...
Date:   Jul 2003
Title:   Leukotriene receptor antagonists for non-cystic fibrosis bronchiectasis
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Leukotriene receptor antagonists are a new class of drug which may have an anti-inflammatory action in some patients with asthma. In theory they may also be of benefit in bronchiectasis, but no randomised controlled trials have yet been reported so it i...
Date:   Jan 2000
Title:   Beclomethasone at different doses for chronic asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Beclomethasone dipropionate (BDP) is available in a wide range of daily doses for the treatment of long-term asthma.
Date:   Jul 1999
Title:   Beclomethasone versus placebo for chronic asthma
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   During an asthma attack, the airways narrow, causing breathing problems, wheezing and coughing. Inhaled corticosteroids (ICS) are used to reduce swelling of the airways. Inhaled beclomethasone dipropionate (BDP) is commonly used. There is now a new form...
Date:   Oct 2004
Title:   Anti-IgE for chronic asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Allergic people produce Immunoglobulin E (IgE) when exposed to environmental allergens, and IgE binds to mast cells in the airways. Acute exposure to the allergen causes mast cells to release chemicals (such as histamine) causing itching, sneezing, bloc...
Date:   Feb 2006
Title:   High dose versus low dose inhaled corticosteroid as initial starting dose for asthma in adults and children
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   People with asthma should start their treatment with low to moderate doses of ICS....
Date:   Aug 2003
Title:   Anticholinergic therapy for chronic asthma in children over two years of age
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Anticholinergic drugs are widely used in the management of both acute and chronic asthma in children. Their effect is achieved through relief of narrowing of the airways that occurs in asthma. Current guidelines for the management of chronic asthma advi...
Date:   Feb 2008
Title:   Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Acute asthma is a common paediatric emergency prevalent in many countries. Treatment aims to reverse asthma by opening up the airways and targeting the underlying inflammation of the airways. Beta-agonists, anticholinergic agents and glucocorticoids are...
Date:   Jan 2005
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