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Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of antibiotic treatments for infections in children.
Created January 2008
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| Title: |
Intraventricular antibiotics for bacterial meningitis in neonates
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Only one trial was identified. In this trial enrolling infants with gram negative meningitis and ventriculitis, the use of intraventricular antibiotics in addition to intravenous antibiotics resulted in a 3 fold increased risk for mortality compared to ...
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| Date: |
Jun 2004
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| Title: |
Face washing promotion for preventing active trachoma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Trachoma is an infectious eye disease. Active infection usually begins in childhood and is characterised by eye discharges, redness and irritation. Poor facial hygiene can lead to the disease spreading from person to person through eye-seeking flies or ...
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| Date: |
Mar 2004
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| Title: |
Antibiotics for preterm rupture of membranes
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Babies born too soon are more likely to suffer ill health in the early days and sometimes throughout life. Early labour and birth (before 37 weeks) may be due to undetected infection. The review found that certain antibiotics given to women, when their ...
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| Date: |
Aug 2004
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| Title: |
Interventions for impetigo
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Impetigo causes blister-like sores. The sores can fill with pus and form scabs, and scratching can spread the infection. Impetigo is caused by bacteria, is contagious and usually occurs in young children. Treatment options include disinfectant solutions...
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| Date: |
Nov 2002
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| Title: |
Antibiotics for acute otitis media in children
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Acute otitis media (infection in the middle ear space) is common in children and causes pain and deafness. The review found that antibiotics did not alter pain within the first day, (when most children were better), only slightly reduced it in the few d...
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| Date: |
Nov 2003
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| Title: |
Antibiotics for treating bacterial vaginosis in pregnancy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Antibiotics during pregnancy for overgrowth of abnormal bacteria in the birth canal does not reduce the risk of babies being born too early....
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| Date: |
Sep 2006
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| Title: |
Interventions for treating genital chlamydia trachomatis infection in pregnancy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Chlamydia is a sexually transmitted infection which, if a mother has it during pregnancy and labour, can cause eye or lung infections in the newborn baby. The risk of transmission during birth varies, but is about 20% to 50% for eye infections and about...
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| Date: |
Jun 1998
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| Title: |
Antibiotics for gonorrhoea in pregnancy
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Neisseria gonorrhoeae is a bacteria transmitted (passed) during sex, causing an infection in the genital area. Pregnant women with gonorrhoea may pass the infection to babies during birth. This can affect the baby's eyesight, causing blindness. The revi...
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| Date: |
Feb 2002
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| Title: |
Short course antibiotics for acute otitis media
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Otitis media (middle ear infection) is very common in childhood, with more than half of all children having at least one infection by the time they are seven. While it seems that usually, otitis media resolves without treatment, it is often treated wit...
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| Date: |
Feb 2000
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| Title: |
Antibiotic regimens for suspected early neonatal sepsis
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Blood infection (sepsis) can make newborn infants seriously ill or even kill them. Sepsis in newborns less than 48 hours old is called early neonatal sepsis. It is usually caused by bacteria passed from the mother. Doctors often give antibiotics if they...
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| Date: |
Jun 2004
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| Title: |
Antibiotics for treating salmonella gut infections
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Antibiotic treatment of salmonella infections aims to shorten illness and prevent serious complications. There are also concerns about increasing antibiotic drug resistance.
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| Title: |
Antibiotics for the prevention of acute and chronic suppurative otitis media in children
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Acute otitis media (infection in the middle ear space) is common in children, causing pain and deafness. This review found that long-term antibiotics (over at least six weeks) almost halved the risk of further infections. There was not enough informatio...
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| Date: |
Jul 2006
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| Title: |
Antibiotics for preventing complications in children with measles
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Measles is an infectious disease caused by a virus. There is an effective vaccine that can prevent measles, however 30 to 40 million people annually still develop measles worldwide. Each year measles causes more than half a million deaths and is respons...
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| Date: |
Jan 2008
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| Title: |
Antibiotics for bronchiolitis in children
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Most cases are thought to be caused by a virus called Respiratory Syncytial Virus (RSV). It is the most common reason for hospitalisation in babies under the age of six months. Despite its viral cause, antibiotics are prescribed in 34 to 99% of cases. T...
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| Date: |
Nov 2006
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| Title: |
Antibiotic regimens for suspected late onset sepsis in newborn infants
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Blood infection (sepsis) can make newborn infants seriously ill or even kill them. Sepsis in newborns more than 48 hours old is called late onset neonatal sepsis; it is usually caused by bacteria, and sometimes by fungal infection. Doctors often give an...
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| Date: |
Mar 2005
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| Title: |
Antibiotics for trachoma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Trachoma is the most common cause of preventable vision loss and is common in children living in poor communities. Repeated bouts of conjunctivitis (inflammation of the membranes of the eyes) caused by chlamydia infection eventually lead to scarring and...
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| Date: |
Feb 2005
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