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Sickle Cell Disease
Sickle cell disease is a genetic disease where the body produces abnormal crescent- or sickle-shaped red blood cells. These cells don't last as long as normal, round red blood cells, which leads to anaemia. The sickle-shaped cells also get stuck in blood vessels, blocking blood flow which can cause pain and organ damage.
Follow the links below to find information about sickle cell disease.
Reviewed March 2011
29 Resources Found
Results 1 to 20 displayed. 1 2
| Title: | Blood transfusions for treating acute chest syndrome in people with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Sickle cell disease is an inherited blood condition affecting over 250 million people worldwide and is particularly common in Sub-Saharan Africa, South and Central America, Saudi Arabia, India and a number of Mediterranean countries. It is characterised... |
| Date: | Sep 2011 |
| Title: | Regular long-term red blood cell transfusions for managing chronic chest complications in sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Oxygen is transported from our lungs to all parts of our body by haemoglobin, which is a major component of red blood cells. Sickle cell disease is an inherited disorder of haemoglobin. In people with sickle cell disease red blood cells become rigid onc... |
| Date: | Aug 2011 |
| Title: | Vaccines for preventing invasive salmonella infections in people with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Salmonella organisms are probably second only to pneumococcus among bacterial causes of infection in people with sickle cell disease. Infection with these bacteria can lead to complications and reduce the quality of life of people with the disease and s... |
| Date: | Jul 2011 |
| Title: | Piracetam for reducing the incidence of painful sickle cell disease crises |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Sickle cell disease is one of the most common genetic disorders and affects about 250 million people (5% of the world's population). It is characterised by sickle-shaped red blood cells which may block blood vessels. This can lead to pain and damage to ... |
| Date: | Mar 2011 |
| Title: | Sickle cell anaemia |
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| Publisher: | Virtual Medical Centre.com |
| Description: | Information on the symptoms, treatment and diagnosis of Sickle cell anaemia by professional health specialists. |
| Date: | Dec 2010 |
| Title: | Antibiotics for treating osteomyelitis in people with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Sickle cell disease affects millions of people throughout the world. Osteomyelitis, a bone infection, is one of the major complications. Antibiotics are given to treat it, but there is no worldwide standard treatment. We did an update of search randomis... |
| Date: | Dec 2010 |
| Title: | Hydroxyurea for sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Haemoglobin is the substance within the red blood cells that carries oxygen around the body. Sickle cell disease (SCD) is an inherited genetic disorder where there are problems with the haemoglobin. Crystals form in the red blood cells and block the blo... |
| Date: | Nov 2010 |
| Title: | Inhaled nitric oxide for acute chest syndrome in people with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Sickle cell disease is an inherited blood disorder affecting approximately 250 million people worldwide. Sickle-shaped red blood cells which are characteristic of sickle cell disease may block blood vessels causing pain, tissue death and even severe dam... |
| Date: | Nov 2010 |
| Title: | Splenectomy versus conservative management for acute sequestration crises in people with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | In some people with sickle cell disease, red blood cells become trapped and destroyed in the spleen. This damages the spleen, which may become enlarged leading to splenic sequestration crises. These crises consist of abdominal pain, rapid heart rate and... |
| Date: | Oct 2010 |
| Title: | Hematopoietic stem cell transplantation for children with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Sickle cell disease is a genetic disorder mainly characterized by the presence of deformed, sickle-shaped red blood cells in the blood stream. These cells deprive tissues of blood and oxygen resulting in periodic and recurrent painful attacks. Complicat... |
| Date: | Oct 2010 |
| Title: | Phytomedicines (medicines derived from plants) for sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Sickle cell disease is an inherited blood condition caused by defects in the production of haemoglobin. Haemoglobin is the part of the red blood cell that carries oxygen across the body. Sickle cell disease occurs when people inherit faulty genes respon... |
| Date: | Sep 2010 |
| Title: | Treatments for priapism in boys and men with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Priapism (the prolonged painful erection of the penis) is common in males with sickle cell disease (SCD). The length of time priapism lasts differs for different types and so does the medical treatment for it. Self-management approaches may be helpful. ... |
| Date: | Aug 2010 |
| Title: | Deferasirox for managing transfusional iron overload in people with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Sickle cell disease is a genetic disorder. An increasing number of people show secondary iron overload due to repeated red blood cell transfusions. Since the human body has no means of actively getting rid of excessive iron, drug treatment (iron chelato... |
| Date: | Jun 2010 |
| Title: | Gene therapy for sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Sickle cell disease results when a child inherits faulty genes for producing haemoglobin from both parents. It is a disease that is linked with frequent illness from early life and often results in death earlier than in the general population. Gene ther... |
| Date: | Jun 2010 |
| Title: | Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | People with sickle cell disease (SCD) are especially prone to respiratory infections and blood poisoning. These infections are often caused by pneumococcal bacteria. Infections occur partly due to the spleen not working correctly, but also because damag... |
| Date: | Apr 2010 |
| Title: | Neonatal screening for sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Sickle cell diseases are inherited and affect mainly people of African origin. The red blood cells are abnormally (sickle) shaped, which can lead to life-threatening complications. They are most likely to be fatal in the first few years of life since af... |
| Date: | Apr 2010 |
| Title: | Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Sickle cell disease is an inherited blood disorder. People with sickle cell disease often suffer from acute chest syndrome, although it is not known why. Acute chest syndrome can cause fever, coughing, chest pain and shortness of breath and can be life-... |
| Date: | Apr 2010 |
| Title: | Fluid replacement therapy for acute episodes of pain in people with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Sickle cell disease is a common genetic disorder characterised by periodic episodes of pain which usually happen again and again throughout life. These episodes occur when sickled cells obstruct blood vessels. The degree of pain may range from a mild di... |
| Date: | Feb 2010 |
| Title: | Treatment for avascular necrosis of bone in people with sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Many people with sickle cell disease experience bone death due to temporary or permanent loss of blood supply to parts of their bones. This can be very painful. The bones usually affected are the thigh bones at the hip joint and the arm bones at the sho... |
| Date: | Jan 2010 |
| Title: | Preoperative blood transfusions for sickle cell disease |
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| Publisher: | John Wiley and Sons, Ltd. for The Cochrane Collaboration |
| Description: | Once they have given up their oxygen, red blood cells in people with sickle cell disease become shaped like crescents. These cells can block blood vessels, which causes problems throughout the body. People with sickle cell disease often need surgery, bu... |
| Date: | Dec 2009 |
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