Clinical Trials

A clinical trial is a particular type of research study using human volunteers to answer specific health questions. Carefully conducted, clinical trials are a reliable way to find treatments that work and ways to improve health. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled circumstances. Observational trials address health issues in large groups of people or for populations in natural settings.

You can find out which clinical trials are taking place in Australia by visiting the Australian New Zealand Clinical Trials Registry at the NHMRC Clinical Trials Centre, University of Sydney.

Follow the links below to find information about clinical trials and randomised controlled trials (RCTs).

Reviewed July 2011

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Participating in Clinical Trials

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Links to information about participating in clinical trials

45 Resources Found

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Title:   Therapeutic Goods Administration (TGA)
Publisher:   Australian Government Department of Health and Ageing
Description:   Home page of Therapeutic Goods Administration (TGA). TGA is Australia's regulatory agency for medical drugs and devices.
Date:   Jan 2012
Title:   Physiotherapy Choices: which treatment is best for me?
Publisher:   Centre for Evidence-Based Physiotherapy (CEBP)
Description:   Physiotherapy Choices is a database designed for use by consumers of physiotherapy services, including patients, their friends and families, health service managers, and insurers. The database provides a catalogue of the best research evidence of the effectiveness of physiotherapy interventions.
Date:   Dec 2011
Title:   PEDro - The Physiotherapy Evidence Database
Publisher:   Centre for Evidence-Based Physiotherapy (CEBP)
Description:   PEDro is the Physiotherapy Evidence Database. It has been developed to give rapid access to bibliographic details and abstracts of randomised controlled trials, systematic reviews and evidence-based clinical practice guidelines in physiotherapy.
Date:   Jan 2012
Title:   The Joanna Briggs Institute
Publisher:   The Joanna Briggs Institute
Description:   Brings together a range of practice-oriented research activities to improve the effectiveness of nursing practice and health care outcomes
Date:   Jan 2012
Title:   Australasian Cochrane Centre
Publisher:   Australasian Cochrane Centre
Description:   The Australasian Cochrane Centre is one of a number of Cochrane centres established worldwide to co-ordinate the activities of the Cochrane Collaboration. It is part of the Monash Institute of Health Services Research, Melbourne, and is funded by the Australian Government Department of Health and Ageing.
Date:   Aug 2011
Title:   PaCCSC
Publisher:   CareSearch
Description:   The Palliative Care Clinical Studies Collaborative (PaCCSC) is a research group looking at improving the quality of care for patients through access, awareness and quality use of palliative care medicines in the community through clinical studies.
Date:   Jun 2011
Title:   Accessing unapproved products
Publisher:   Australian Government Department of Health and Ageing
Description:   There are a number of ways that patients can gain access to products that have not been approved for use in Australia.
Date:   Apr 2011
Title:   Clinical trials
Publisher:   The Cancer Council Victoria
Description:   Clinical trials take laboratory research results and translate them to a clinical setting. Trials are an important final step in a long process to prove the effectiveness and safety of cancer treatments.
Date:   Mar 2011
Title:   New drugs:T-score for transparency
Publisher:   Australian Prescriber
Description:   To encourage transparency, Australian Prescriber rates companies' willingness to provide clinical information about new drugs.
Date:   Feb 2011
Title:   Randomisation to protect against selection bias in healthcare trials
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Randomised controlled trials (RCTs) use the play of chance to allocate participants to comparison groups to prevent selection bias. Other means of treatment allocation are more prone to bias because decisions about which treatment to use can be influenc...
Date:   Dec 2010
Title:   Comparison of protocols and registry entries to published reports for randomised controlled trials
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The non-reporting of a piece of research and the selective reporting of only some of its findings has been identified as a problem for research studies such as randomised trials and systematic reviews of these. If the decision about what to report and w...
Date:   Nov 2010
Title:   Placebo effect
Publisher:   Better Health Channel
Description:   A placebo is any medical treatment that is inert (inactive), such as a sugar pill. Around one third of people who take placebos (believing them to be medication) will experience an end to their symptoms. This is called the placebo effect.
Date:   Oct 2010
Title:   Research and Innovation
Publisher:   Novita Children's Services
Description:   Introduction to research conducted at Novita Children's Services.
Date:   Jul 2010
Title:   Ovarian cancer: choosing treatment - myDr.com.au
Publisher:   myDr
Description:   Find out how you can choose the right treatment for ovarian cancer and about clincial trials.
Date:   Jul 2010
Title:   Strategies to improve recruitment to randomised controlled trials
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Many trials do not recruit sufficient participants and this can make it more difficult to use the results of the research in practice. Effective strategies for improving recruitment would be of great benefit to researchers designing and running trials. ...
Date:   Jun 2010
Title:   Clinical trials
Publisher:   Cancer Australia
Description:   Clinical trials with cancer patients try to find out whether new approaches to cancer prevention, diagnosis and treatment are safe and effective. Clinical trials can study new drugs, different doses of the same drug, surgical techniques, radiotherapy, or how cancer services are delivered.
Date:   Jul 2009
Title:   Hep C Treatment Snapshot
Publisher:   Haemophilia Foundation Australia
Description:   An update on current hepatitis C treatments and treatment experiences of people with bleeding disorders and hepatitis C.
Date:   May 2009
Title:   NCOR - neoadjuvant chemotherapy in ovarian cancer: a systematic review
Publisher:   Cancer Australia
Description:   A systematic review has been undertaken to identify evidence for the administration of neoadjuvant chemotherapy before cytoreductive surgery is performed.
Date:   May 2009
Title:   Surrogate outcome markers in research and clinical practice
Publisher:   Australian Prescriber
Description:   There are some valid surrogate markers of disease progression which can be reliably used to monitor chronic conditions, and as treatment goals. However, the clinical utility of many surrogates is open to question and their validity is largely untested.
Date:   Apr 2009
Title:   ARPANSA - Code of practice for the exposure of humans to ionizing radiation for research purposes (2005)
Publisher:   Australian Radiation Protection and Nuclear Safety Agency (ARPANSA)
Description:   This Code of Practice is designed to ensure that researchers proposing to expose research participants to ionizing radiation provide the participants and the Human Research Ethics Committees with information that allows consent to be properly considered by the research participants and approval considered by the Human Research Ethics Committee.
Date:   Feb 2009

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