Clinical Trials

A clinical trial is a particular type of research study of human volunteers to answer specific health questions. Carefully conducted, clinical trials are a reliable way to find treatments that work in people and ways to improve health. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments. Observational trials address health issues in large groups of people or populations in natural settings.

You can find out which clinical trials are taking place in Australia by visiting the Australian New Zealand Clinical Trials Registry at the NHMRC Clinical Trials Centre, University of Sydney.

Follow the links below to find information about clinical trials and randomised controlled trials (RCTs).

Reviewed December 2007

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Participating in Clinical Trials
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Links to information about participating in clinical trials
47 Resources Found
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Title:   TGA - Therapeutic Goods Administration
Publisher:   Australian Government Department of Health and Ageing
Description:   Home page of Therapeutic Goods Administration (TGA). TGA is Australia's regulatory agency for medical drugs and devices.
Date:   Aug 2008
Title:   Australasian Cochrane Centre
Publisher:   Australasian Cochrane Centre
Description:   The Australasian Cochrane Centre is one of a number of Cochrane centres established worldwide to co-ordinate the activities of the Cochrane Collaboration. It is part of the Monash Institute of Health Services Research, Melbourne. and is funded by the Australian Commonwealth Department of Health and Ageing.
Date:   Aug 2008
Title:   The Joanna Briggs Institute
Publisher:   The Joanna Briggs Institute
Description:   Brings together a range of practice-oriented research activities to improve the effectiveness of nursing practice and health care outcomes
Date:   Jun 2008
Title:   PEDro - The Physiotherapy Evidence Database
Publisher:   Centre for Evidence-Based Physiotherapy (CEBP)
Description:   PEDro is the Physiotherapy Evidence Database. It has been developed to give rapid access to bibliographic details and abstracts of randomised controlled trials, systematic reviews and evidence-based clinical practice guidelines in physiotherapy.
Date:   Jun 2008
Title:   Neoadjuvant chemotherapy in ovarian cancer: a systematic review
Publisher:   National Breast and Ovarian Cancer Centre (NBOCC),National Breast Cancer Centre (NBCC)
Description:   A systematic review has been undertaken to identify evidence for the administration of neoadjuvant chemotherapy before cytoreductive surgery is performed.
Date:   Apr 2008
Title:   Interpreting risks and ratios in therapy trials
Publisher:   Australian Prescriber
Description:   In randomised trials and systematic reviews of trials, the effects of new treatments on dichotomous outcomes can be expressed in several ways including relative risk, absolute risk, odds ratio and hazard ratio.
Date:   Feb 2008
Title:   Audio-visual presentation of information for informed consent for participation in clinical trials
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Informed consent is important for people who are thinking about participating in a clinical trial. Information for informed consent could be presented on the Internet, DVD, video cassette or by other means. ...
Date:   Nov 2007
Title:   Clinical research
Publisher:   Novita Children's Services
Description:   Information is provided about the extensive research being undertaken by Novita into clinical practice and general service effectiveness.
Date:   Sep 2007
Title:   Media release. $15.4 million for new palliative care initiatives
Publisher:   Australian Government Department of Health and Ageing
Description:   The Australian Government today announced more than $15 million in funding for two new palliative care initiatives.
Date:   Aug 2007
Title:   About clinical trials
Publisher:   The Cancer Council Victoria
Description:   Clinical trials test new cancer treatment methods against current practices.
Date:   Jun 2007
Title:   Placebo effect
Publisher:   Better Health Channel
Description:   A placebo is any medical treatment that is inert, such as a sugar pill. Around one third of people who take placebos (believing them to be medication) will experience an end to their symptoms. This is called the placebo effect.
Date:   Mar 2007
Title:   National statement on ethical conduct in research involving humans
Publisher:   National Health and Medical Research Council (NHMRC)
Description:   The purpose of this Statement is to provide a national reference point for ethical consideration relevant to all research involving humans. It identifies the ethical principles and values which should govern research involving humans.
Date:   Mar 2007
Title:   The Australian and New Zealand Clinical Trials Registry
Publisher:   National Health and Medical Research Council (NHMRC)
Description:   The Australian and New Zealand Clinical Trials Registry is a national on-line registry of all types of clinical trials being undertaken in Australia
Title:   How prescription drugs are developed
Publisher:   Australian Prescriber
Description:   Modern drug development is a risky business both for pharmaceutical companies and patients. Many thousands of promising compounds need to be tested.
Date:   Dec 2006
Title:   Australian Government Response to the recommendations of the review of clinical trials and access to unapproved therapeutic goods (Bansemer Report) July 2006
Publisher:   Australian Government Department of Health and Ageing
Description:   This document details the Australian Government response to the recommendations made by an independent, external review of the Australian arrangements for clinical trials and access to unapproved therapeutic goods.
Date:   Nov 2006
Title:   Beyond critical appraisal
Publisher:   Australian Prescriber
Description:   A key foundation of evidence-based medicine (EBM) is that clinicians with appropriate training can critically appraise research papers.
Date:   Oct 2006
Title:   The Australian clinical trial handbook
Publisher:   Australian Government Department of Health and Ageing
Description:   A simple, practical guide to the conduct of clinical trials to International standards of Good Clinical Practice (GCP) in the Australian context.
Date:   Mar 2006
Title:   Understanding the latest research on hormone replacement therapy (HRT)
Publisher:   Women's Health Victoria (WHV)
Description:   Discusses the study on hormone replacement therapy by Women's Health Initiative (WHI) in the United States that was cut short due to the findings of increased risk of some health problems. Discusses the study on HRT and the effect on dementia and memory
Date:   Mar 2006
Title:   Everyone's medicines experience can help everyone
Publisher:   Consumers' Health Forum of Australia (CHF)
Description:   Working together to link datasets in a useable manner that protects patient privacy and confidentiality is a priority for using medicines data already available to help everyone.
Date:   Jan 2006
Title:   ARPANSA - Code of practice for the exposure of humans to ionizing radiation for research purposes (2005)
Publisher:   Australian Radiation Protection and Nuclear Safety Agency (ARPANSA)
Description:   This Code of Practice is designed to ensure that researchers proposing to expose research participants to ionizing radiation provide the participants and the Human Research Ethics Committees with information that allows consent to be properly considered by the research participants and approval considered by the Human Research Ethics Committee.
Date:   Jun 2005
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